06-944
Anti-TPOR/c-Mpl Antibody
Upstate®, from rabbit
Synonyme(s) :
Anti-C-MPL, Anti-MPLV, Anti-THCYT2, Anti-THPOR, Anti-TPOR
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A propos de cet article
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, IP, WB
Citations:
14
Service technique
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Laissez-nous vous aiderbiological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, human
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... MPL(4352)
mouse ... Mpl(17480)
General description
68.5 kDa (calculated)
Immunogen
KLH-conjugated, synthetic peptide corresponding to amino acids 615-628 of human TPO (thrombopoietin) receptor (C-ANHSYLPLSYWQQP)
Application
Anti-TPOR/c-Mpl Antibody is an antibody against TPOR/c-Mpl for use in IP, WB, IH.
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Biochem/physiol Actions
glycosylated and unglycosylated TPO receptor/c-Mpl
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography
Preparation Note
2 years at -20°C
Analysis Note
routinely evaluated by immunoblot on RIPA lysates from DAMI cells
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Classe de stockage
10 - Combustible liquids
wgk
WGK 1
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Reiji Nozaki et al.
Hepatology research : the official journal of the Japan Society of Hepatology, 43(6), 610-620 (2012-11-20)
Liver cirrhosis (LC) is the end stage of chronic liver disease. No definitive pharmacological treatment is currently available. We previously reported that thrombopoietin (TPO) promoted liver regeneration and improved liver cirrhosis by increasing platelet count. TPO is therefore considered to
Cédric Cleyrat et al.
Traffic (Copenhagen, Denmark), 15(9), 961-982 (2014-06-17)
Myeloproliferative neoplasms (MPNs) are often characterized by JAK2 or calreticulin (CALR) mutations, indicating aberrant trafficking in pathogenesis. This study focuses on Mpl trafficking and Jak2 association using two model systems: human erythroleukemia cells (HEL; JAK2V617F) and K562 myeloid leukemia cells
Norma E Fox et al.
Experimental hematology, 37(4), 495-503 (2009-03-24)
To genetically and functionally characterize mutations of c-Mpl that lead to thrombocytopenia in a child with congenital amegakaryocytic thrombocytopenia. We identified two c-Mpl mutations in a child with clinical features of congenital amegakaryocytic thrombocytopenia, one a previously described mutation in
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| 06-944 | 04053252506765 |