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Merck

07-580

Anti-IKKε Antibody

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Nom du produit

Anti-IKKε Antibody, Upstate®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_014002

UniProt accession no.

Q14164

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... IKBKE(9641)
mouse ... Ikbke(56489)

Application

Research Category
Signaling
Research Sub Category
Immunological Signaling
This Anti-IKKε Antibody is validated for use in WB for the detection of IKKε.

Biochem/physiol Actions

IKKε

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Mr 80kDa

Immunogen

KLH-conjugated, synthetic peptide corresponding to amino acids 582-596 (SHLAKRLLQVFQEEC) of human IKKε

Physical form

Format: Purified
Protein A purified
of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

Preparation Note

Stable for 2 years at -20°

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Classe de stockage

10 - Combustible liquids

wgk

WGK 1

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Consulter la Bibliothèque de documents

Vladimir V Kravchenko et al.
The Journal of biological chemistry, 278(29), 26612-26619 (2003-05-09)
We report that the product of the inducible gene encoding the kinase known as IKKi/IKKepsilon (IKKi) is required for expression of a group of genes up-regulated by pro-inflammatory stimuli such as bacterial endotoxin (lipopolysaccharide (LPS)). Here, using murine embryonic fibroblasts
Lídia Hernandez et al.
Cancer research, 70(10), 4005-4014 (2010-04-29)
The NF-kappaB family of transcription factors has been implicated in the propagation of ovarian cancer, but the significance of constitutive NF-kappaB signaling in ovarian cancer is unknown. We hypothesized that constitutive NF-kappaB signaling defines a subset of ovarian cancer susceptible
Tina Ruggiero et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(9), 2898-2908 (2009-05-09)
The importance of post-transcriptional mechanisms for the regulation of the homoeostasis of the immune system and the response to challenge by microorganisms is becoming increasingly appreciated. We investigated the contribution of microRNAs (miRNAs) to macrophage activation induced by lipopolysaccharide (LPS).
Congwen Wei et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(5), E601-E610 (2014-01-23)
Resistance to antiestrogens is one of the major challenges in breast cancer treatment. Although phosphorylation of estrogen receptor α (ERα) is an important factor in endocrine resistance, the contributions of specific kinases in endocrine resistance are still not fully understood.

Numéro d'article de commerce international

RéférenceGTIN
07-58004053252472947

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