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Merck

1.03893

Acide benzènesulfonique

EMPROVE® EXPERT

Synonyme(s) :

Benzene sulphonic acid, Benzenesulphonic acid, Besylic acid, Phenylsulfonic acid, Phenylsulphonic acid

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A propos de cet article

Formule linéaire :
C6H5SO3H
Numéro CAS:
Poids moléculaire :
158.18
EC Number:
202-638-7
UNSPSC Code:
12352005
MDL number:
Beilstein/REAXYS Number:
742513
Service technique
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biological source

synthetic

Quality Level

product line

EMPROVE® EXPERT

form

crystalline

technique(s)

API processing | cocrystal formation: suitable, API processing | salt formation: suitable

impurities

endotoxins, low

application(s)

liquid formulation
parenterals
pharmaceutical

storage temp.

15-25°C

SMILES string

OS(=O)(=O)c1ccccc1

InChI

1S/C6H6O3S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H,7,8,9)

InChI key

SRSXLGNVWSONIS-UHFFFAOYSA-N

General description

For protein-based therapeutics, such as monoclonal antibodies (mAbs) or plasma derived proteins, often highly concentrated protein formulations are required to meet intended dosing regimens. However, this usually comes with elevated viscosities and presents a challenge in the manufacturing process and final formulation. Our Viscosity Reduction Excipient Platform reduces the viscosity and helps overcome challenges associated with highly concentrated protein solutions.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation.
Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

The Viscosity Reduction Platform is based on the combination of two new excipients, one amino acid component with one anionic component, that together can better reduce protein viscosity beyond levels achieved with single excipients. Also, combining the two components enables a balance of viscosity reduction and protein stabilization. Benzenesulfonic Acid Emprove® Expert is part of this new proprietary technology platform.

Packaging

1038930500 / 500g / Glass bottle
1038931000 / 1kg / Glass bottle

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany


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pictograms

CorrosionExclamation mark

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Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Classe de stockage

8A - Combustible corrosive hazardous materials



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