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Merck

14-198

MAP Kinase 2/Erk2 Protein, inactive, Mouse, 50 g

Unactive, recombinant full-length mouse p42 MAP Kinase 2/Erk2 fused with GST at the N terminus, for use in Kinase Assays.

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A propos de cet article

UNSPSC Code:
12352202
NACRES:
NA.41
eCl@ss:
32160405
Biological source:
mouse
Recombinant:
expressed in E. coli
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biological source

mouse

recombinant

expressed in E. coli

mol wt

Mw 67.8 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Quality Level

General description

Product Source: expressed in E coli
Recombinant full-length mouse p42 MAP Kinase 2/Erk2 fused with GST at the N terminus

Analysis Note

routinely evaluated by phosphorylation of MBP (Catalog # 13-104) substrate in vitro.

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

Classe de stockage

10 - Combustible liquids

wgk

WGK 2


Certificats d'analyse (COA)

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Tian-Rui Xu et al.
The Biochemical journal, 413(1), 51-60 (2008-04-26)
FRET (fluorescence resonance energy transfer) and co-immunoprecipitation studies confirmed the capacity of beta-arrestin 2 to self-associate. Amino acids potentially involved in direct protein-protein interaction were identified via combinations of spot-immobilized peptide arrays and mapping of surface exposure. Among potential key
Maofu Fu et al.
Methods in molecular biology (Clifton, N.J.), 284, 15-36 (2004-06-03)
Signal transduction pathways mediate cell-cell interactions and integrate signals from the extracellular environment through specific receptors at the cell membrane. They play a pivotal role in regulating cellular growth and differentiation and in mediating many physiological and pathological processes, such
Okano J et al.
The Journal of biological chemistry, 276(22), 19555-19564 (2001-03-30)
Paclitaxel is a widely used chemotherapeutic agent and is known to induce programmed cell death (apoptosis) in a variety of cell types, but the precise underlying mechanisms are poorly understood. To elucidate these mechanisms, we challenged human esophageal squamous cancer
D Aronson et al.
The Journal of biological chemistry, 272(41), 25636-25640 (1997-11-05)
Contractile activity plays a critical role in the regulation of gene transcription in skeletal muscle, which in turn determines muscle functional capabilities. However, little is known about the molecular signaling mechanisms that convert contractile activity into gene regulatory responses in
O Zugasti et al.
Molecular and cellular biology, 21(19), 6706-6717 (2001-09-05)
Signals from the extracellular matrix are essential for the survival of many cell types. Dominant-negative mutants of two members of Rho family GTPases, Rac1 and Cdc42, mimic the loss of anchorage in primary mouse fibroblasts and are potent inducers of

Numéro d'article de commerce international

RéférenceGTIN
14-19804053252506833

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