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Merck

14-309

PCAF Protein, Active, 50 µg

PCAF recombinant GST fusion protein, for use in Histone Acetyltransferase Assays. (HAT).

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A propos de cet article

UNSPSC Code:
12352202
NACRES:
NA.32
eCl@ss:
32160405
Recombinant:
expressed in E. coli
Mol wt:
Mw 79 kDa
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recombinant

expressed in E. coli

mol wt

Mw 79 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (histone acetyltransferase (HAT))

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Quality Level

General description

Product Source: expressed in E. Coli corresponding to amino acids 352-832

Analysis Note

routinely evaluated by acetylation of core histones in vitro

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Classe de stockage

10 - Combustible liquids

wgk

WGK 1


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Giosalba Burgio et al.
Journal of enzyme inhibition and medicinal chemistry, 31(sup3), 75-82 (2016-07-09)
Histones and polyamines are important determinants of the chromatin structure. Histones form the core of nucleosome particles and their modification by acetylation of N-terminal tails is involved in chromatin structural changes and transcriptional regulation. Polyamines, including spermidine, are also targets
Prabhat Kumar Purbey et al.
Molecular and cellular biology, 29(5), 1321-1337 (2008-12-24)
Special AT-rich binding protein 1 (SATB1) acts as a global regulator of gene expression by recruiting various corepressor or coactivator complexes, thereby establishing a unique chromatin structure at its genomic targets in a context-dependent manner. Although SATB1 acts predominantly as
Matteo Savoia et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(3), 4107-4123 (2018-12-12)
The epigenetic enzyme p300/CBP-associated factor (PCAF) belongs to the GCN5-related N-acetyltransferase (GNAT) family together with GCN5. Although its transcriptional and post-translational function is well characterized, little is known about its properties as regulator of cell metabolism. Here, we report the
Chromosomal protein HMGN1 enhances the acetylation of lysine 14 in histone H3.
Jae-Hwan Lim,Katherine L West,Yaffa Rubinstein,Michael Bergel,Yuri V Postnikov,Michael Bustin
The Embo Journal null
Steven E Lang et al.
Oncogene, 22(18), 2836-2841 (2003-05-14)
The adenovirus E1A oncoprotein stimulates cell growth and inhibits differentiation by deregulating the normal transcription program via interaction with positive and negative cellular effectors. E1A associates with transcriptional regulatory complexes containing p400 and TRRAP involved in chromatin remodeling and decondensation.

Numéro d'article de commerce international

RéférenceGTIN
14-30904053252586798

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