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Merck

178479

Anti-Apolipoprotein E Goat pAb

liquid, Calbiochem®

Synonyme(s) :

Anti-ApoE antibody

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A propos de cet article

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human, rat, mouse
Application:
Citations:
57
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biological source

goat

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human, rat, mouse

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(ELISA (1:8000)
Immunoprecipitation
Free Floating Sections )

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Application

ELISA (1:8000)

Immunoprecipitation (see comments)

Free Floating Sections (see application references)

Disclaimer

Toxicity: Standard Handling (A)

General description

Anti-Apolipoprotein E, goat polyclonal, recognizes human apolipoprotein E. Does not cross-react with other apolipoproteins. It is validated for ELISA, immunoprecipitation, and free-floating sections.
Goat polyclonal antibody supplied as serum that has been defibrinated, delipidized and dialyzed against a Tris-HCl buffer. Recognizes the apolipoprotein E protein.
Recognizes human apolipoprotein E. Does not cross-react with other apolipoproteins.
  • Antibody Target Gene Symbol: APOE
  • Target Synonym: AD2, AI255918, APOE2, APOE4, APOEA, APOLIPOPROTEIN E, LDLCQ5, LPG, MGC1571
  • Entrez Gene Name: apolipoprotein E
  • Hu Entrez ID: 348 (Related Antibodies: NE1004)
  • Mu Entrez ID: 11816
  • Rat Entrez ID: 25728
  • Immunogen

    Human
    purified recombinant human apolipoprotein E

    Other Notes

    Monospecific as determined by immunoelectrophoresis (IEP) against twice concentrated pooled human serum. This antibody has also been reported to work with immunoprecipitation. Variables associated with assay conditions will dictate the proper working dilution.

    Packaging

    Please refer to vial label for lot-specific concentration.

    Physical form

    In 500 mM NaCl, 50 mM Tris-HCl, pH 7.5.

    Preparation Note

    Following initial thaw, aliquot and freeze (-20°C).

    Legal Information

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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    Classe de stockage

    10 - Combustible liquids

    wgk

    WGK 1

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable


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    Consulter la Bibliothèque de documents

    Jin-Dong Ding et al.
    Proceedings of the National Academy of Sciences of the United States of America, 108(28), E279-E287 (2011-06-22)
    Age-related macular degeneration (AMD) is a leading cause of visual dysfunction worldwide. Amyloid β (Aβ) peptides, Aβ1-40 (Aβ40) and Aβ1-42 (Aβ42), have been implicated previously in the AMD disease process. Consistent with a pathogenic role for Aβ, we show here
    Emilie L Castranio et al.
    Neurobiology of disease, 105, 1-14 (2017-05-16)
    Traumatic brain injury (TBI) is strongly linked to an increased risk of developing dementia, including chronic traumatic encephalopathy and possibly Alzheimer's disease (AD). APOEε4 allele of human Apolipoprotein E (APOE) gene is the major genetic risk factor for late onset
    Elizabeth S Chan et al.
    Scientific reports, 6, 26119-26119 (2016-05-18)
    The apolipoprotein E4 (ApoE4) is the strongest genetic risk factor for Alzheimer's disease (AD). The AD brain was shown to be insulin resistant at end stage, but the interplay between insulin signaling, ApoE4 and Aβ across time, and their involvement
    Xiao-Juan Cheng et al.
    PloS one, 10(6), e0130432-e0130432 (2015-06-16)
    Recent studies suggest that high-salt diet is associated with cognitive decline in human and mouse. The fact that genetic factors account for less than 50% cases of sporadic Alzheimer's disease (AD) highlights the important contribution of environmental factors, such as
    Daniel Da Costa et al.
    Journal of virology, 86(21), 11919-11925 (2012-08-17)
    Hepatitis C virus (HCV) is a human hepatotropic virus, but the relevant host factors restricting HCV infection to hepatocytes are only partially understood. We demonstrate that exogenous expression of defined host factors reconstituted the entire HCV life cycle in human

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