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Merck

AB15452

Anti-MAP2 Antibody

CHEMICON®, chicken polyclonal

Synonyme(s) :

Microtubule associated protein 2

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A propos de cet article

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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Nom du produit

Anti-MAP2 Antibody, Chemicon®, from chicken

biological source

chicken

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

mouse ... Map2(17756)

Application

Anti-MAP2 Antibody detects level of MAP2 & has been published & validated for use in IC, IH.
Immunohistochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed tissue.

Immunocytochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed cells.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurofilament & Neuron Metabolism

Biochem/physiol Actions

MAP2 [Microtubule associated protein 2]
Other species have not yet been tested. It is expected that the antibody will also react with human due to immunogen sequence similarity.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Synthetic peptides corresponding to different regions of the human/mouse MAP2 protein.

Physical form

Affinity purified chicken immunoglobulin. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.
ImmunoAffinity Purified

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Classe de stockage

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Yun Yang et al.
Nature communications, 13(1), 159-159 (2022-01-12)
Abnormalities in brain glucose metabolism and accumulation of abnormal protein deposits called plaques and tangles are neuropathological hallmarks of Alzheimer's disease (AD), but their relationship to disease pathogenesis and to each other remains unclear. Here we show that succinylation, a
Andrew R Snavely et al.
Disease models & mechanisms, 15(12) (2022-11-19)
The proteosome inhibitor bortezomib has revolutionized the treatment of multiple hematologic malignancies, but in many cases, its efficacy is limited by a dose-dependent peripheral neuropathy. We show that human induced pluripotent stem cell (hiPSC)-derived motor neurons and sensory neurons provide
Hae-Jin Kweon et al.
Cell reports, 32(6), 108025-108025 (2020-08-14)
The α7 nicotinic acetylcholine receptor participates in diverse aspects of brain physiology and disease. Neurons tightly control α7 assembly, which relies upon NACHO, an endoplasmic reticulum (ER)-localized integral membrane protein. By constructing α7 chimeras and mutants, we find that NACHO
Madhurima Dhara et al.
Nature communications, 11(1), 2799-2799 (2020-06-05)
Small molecule polyamines are abundant in all life forms and participate in diverse aspects of cell growth and differentiation. Spermidine/spermine acetyltransferase (SAT1) is the rate-limiting enzyme in polyamine catabolism and a primary genetic risk factor for suicidality. Here, using genome-wide
Sarra Djemil et al.
Journal of neurochemistry, 153(4), 468-484 (2019-12-11)
Nicotinic acetylcholine receptors (nAChRs) are known to play a role in cognitive functions of the hippocampus, such as memory consolidation. Given that they conduct Ca2+ and are capable of regulating the release of glutamate and γ-aminobutyric acid (GABA) within the

Numéro d'article de commerce international

RéférenceGTIN
AB1545204053252405099

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