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Merck

AB9042

Anti-Brain Derived Neurotrophic Factor Antibody, pro

Chemicon®, from chicken

Synonyme(s) :

proBDNF, pro BDNF

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, IP, WB
Citations:
9
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biological source

chicken

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... BDNF(627)

Immunogen

Fusion protein from mouse proBDNF containing only the prodomain region.

Application

Anti-Brain Derived Neurotrophic Factor Antibody, pro detects level of Brain Derived Neurotrophic Factor & has been published & validated for use in IP, WB, IH.
Western blot: 1:500-1:1,000. Reacts with bands of 30 kD and 28 kD.Immunohistochemistry: 1:100-1:250 on frozen sections.

Immunohistochemistry: 1:100-1:200

Immunoprecipitation: 1:100

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Reacts with proBDNF. Does not recognize mature BDNF isoforms.

Physical form

Chicken immunoglobulin. Liquid.
Format: Semi-Purified

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


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Classe de stockage

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Working memory deficits, increased anxiety-like traits, and seizure susceptibility in BDNF overexpressing mice.
Papaleo, F; Silverman, JL; Aney, J; Tian, Q; Barkan, CL; Chadman, KK; Crawley, JN
Learning & Memory null
Alta Berger et al.
Endocrinology, 157(2), 600-610 (2015-12-17)
In both mice and patients with Albright hereditary osteodystrophy, heterozygous inactivating mutations of Gsα, a ubiquitously expressed G protein that mediates receptor-stimulated intracellular cAMP production, lead to obesity and insulin resistance but only when the mutation is present on the
Heejung Chun et al.
Experimental neurobiology, 27(3), 155-170 (2018-07-20)
Astrocytes are the most abundant cell type in the brain and they make close contacts with neurons and blood vessels. They respond dynamically to various environmental stimuli and change their morphological and functional properties. Both physiological and pathological stimuli can



Numéro d'article de commerce international

RéférenceGTIN
AB904204053252673214