AB9206
Anti-DARPP-32 Antibody, phosphoThr34
Chemicon®, from rabbit
Synonyme(s) :
Anti-DARPP-32, Anti-DARPP32
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A propos de cet article
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
human, mouse, rat
Application:
WB
Citations:
2
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Laissez-nous vous aiderbiological source
rabbit
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, mouse, rat
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
phosphorylation (pThr34)
Quality Level
Gene Information
human ... PPP1R1B(84152)
General description
~32 kD
Immunogen
Epitope: phosphoThr34
Synthetic peptide from DARPP-32, phosphoThr34.
Application
Research Category
Neuroscience
Neuroscience
Research Sub Category
Reward & Addiction
Signaling Neuroscience
Reward & Addiction
Signaling Neuroscience
This Anti-DARPP-32 Antibody, phosphoThr34 is validated for use in WB for the detection of DARPP-32.
Western blot: 1:1,000. The antibody recognizes the ~32 kD DARPP-32 protein phosphorylated at Thr34 protein in rat caudate lysate prepared from caudate slices that had been incubated in the absence and presence of forskolin. The labeling by the antibody to DARPP-32 Thr34 is markedly increased by the forskolin treatment.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes DARPP-32 phosphorylated at threonine 34 .
Physical form
Affinity Purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg per mL BSA with 50% glycerol.
ImmunoAffinity Purified
Preparation Note
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Cultured primary neurons, rat brain lysate and human breast adenocarcinoma
Cultured primary neurons, rat brain lysate and human breast adenocarcinoma
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Classe de stockage
10 - Combustible liquids
wgk
WGK 2
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Lídia Cantacorps et al.
British journal of pharmacology, 177(5), 1090-1105 (2019-11-11)
Alcohol exposure in utero may lead to a wide range of long-lasting morphological and behavioural deficiencies known as fetal alcohol spectrum disorders (FASD), associated with a higher risk of later developing neuropsychiatric disorders. However, little is known about the long-term
Maria De Risi et al.
Nature communications, 12(1), 3495-3495 (2021-06-11)
Lysosomal storage disorders characterized by altered metabolism of heparan sulfate, including Mucopolysaccharidosis (MPS) III and MPS-II, exhibit lysosomal dysfunctions leading to neurodegeneration and dementia in children. In lysosomal storage disorders, dementia is preceded by severe and therapy-resistant autistic-like symptoms of
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| AB9206 | 04053252626210 |
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