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Merck

CBL468

Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6

clone HC1/6, Chemicon®, from mouse

Synonyme(s) :

CD31

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
HC1/6, monoclonal
Application:
FACS, IHC (p), IP
Citations:
15
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

clone

HC1/6, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunoprecipitation (IP): suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PECAM1(5175)

Immunogen

Epitope: domains 3-6 of human PECAM-1

Application

Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6 is an antibody against PECAM-1 for use in FC, IH, IH(P) & IP.
Studies of the role of CD31 in leucocyte migration into inflammatory sites and in the process of angiogenesis

This antibody will stain frozen tissue sections

Suitable for immunoprecipitation studies

Suitable for flow cytometry either indirectly or directly when labelled with FITC or R-PE

Suitable for use on formalin fixed paraffin embedded sections after protease pre-treatment.

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Reacts with a 130-140 kDa transmembranous glycoprotein that is expressed widely amongst cells of the vascular compartment. CD31 is expressed on platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney as well as in skin biopsies from conditions such as sarcoidosis and lepromatous leprosy.
FUSION PARTNER: P3-x63Ag8.653 myeloma cell line

Physical form

Format: Purified

Analysis Note

Control
Activated microglial cells

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


Classe de stockage

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificats d'analyse (COA)

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Fumiko Obata et al.
Toxins, 14(2) (2022-02-25)
Shiga toxin-producing Escherichia coli (STEC) causes proximal tubular defects in the kidney. However, factors altered by Shiga toxin (Stx) within the proximal tubules are yet to be shown. We determined Stx receptor Gb3 in murine and human kidneys and confirmed
Yu-Ting Huang et al.
Cellular signalling, 20(8), 1521-1527 (2008-05-27)
Sphingosine 1-phosphate (S1P) is a multifunctional phospholipid which acts through a specific family of G protein-coupled receptors. Platelet/endothelial cell adhesion molecule-1 (PECAM-1) form trans-homophilic binding at lateral cell border. Upon stimulation, its cytoplasmic tyrosine residues could be phosphorylated and interact
Guiting Lin et al.
Stem cells and development, 17(6), 1053-1063 (2008-07-04)
Adipose tissue-derived stem cells (ADSC) are routinely isolated from the stromal vascular fraction (SVF) of homogenized adipose tissue. Freshly isolated ADSC display surface markers that differ from those of cultured ADSC, but both cell preparations are capable of multipotential differentiation.



Numéro d'article de commerce international

RéférenceGTIN
CBL46804053252331015