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Merck

MAB1876

Anti-Integrin αVβ6 Antibody

CHEMICON®, mouse monoclonal, 27.1 (VNR-1)

Synonyme(s) :

CD51/CD61, VNR-1

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A propos de cet article

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
27.1 (VNR-1), monoclonal
Species reactivity:
human
Application:
IF, IP
Citations:
4

Principaux documents

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Nom du produit

Anti-Integrin αVβ3 Antibody, clone 27.1 (VNR-1), clone 27.1 (VNR-1), Chemicon®, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

27.1 (VNR-1), monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable, immunoprecipitation (IP): suitable

isotype

IgG1

NCBI accession no.

NM_002210.2

UniProt accession no.

P06756

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... ITGAV(3685)

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Application

Anti-Integrin αVβ3 Antibody, clone 27.1 (VNR-1) detects level of Integrin αVβ3 & has been published & validated for use in IF & IP.
Immunohistochemistry: 4-10% formalin fixed frozen tissues (short fixation times, 10 minutes room temperature) only; not effective on paraffin embedded tissues

Immunoprecipitation

Functional blocking: Competes with clone LM609 for integrin function blocking.



Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Biochem/physiol Actions

Reacts with the human integrin alphaVbeta3. Shown to be specific for alphaVbeta3 by Loftus JC et al (1990) Science 249:915-918.

Physical form

Format: Purified
Protein A purified mouse immunoglobulin in liquid in 0.02M PB, pH 7.6, 0.25M NaCl containing 0.1% sodium azide.

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Classe de stockage

12 - Non Combustible Liquids

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Dake Hao et al.
Frontiers in bioengineering and biotechnology, 8, 890-890 (2020-08-28)
Endothelial cell (EC) transplantation via injectable collagen hydrogel has received much attention as a potential treatment for various vascular diseases. However, the therapeutic effect of transplanted ECs is limited by their poor viability, which partially occurs as a result of
Handong Ma et al.
Cell reports, 30(3), 793-806 (2020-01-23)
Periostin is a multifunctional extracellular matrix protein involved in various inflammatory diseases and tumor metastasis; however, evidence regarding whether and how periostin actively contributes to inflammation-associated tumorigenesis remains elusive. Here, we demonstrate that periostin deficiency significantly inhibits the occurrence of
Kouki Morizono et al.
Journal of virology, 88(8), 4275-4290 (2014-01-31)
We recently demonstrated that a soluble protein, Gas6, can facilitate viral entry by bridging viral envelope phosphatidylserine to Axl, a receptor tyrosine kinase expressed on target cells. The interaction between phosphatidylserine, Gas6, and Axl was originally shown to be a

Numéro d'article de commerce international

RéférenceGTIN
MAB187604053252616778

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