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Merck

MAB2258

Anti-Syntaxin-3 Antibody, clone 1-146

clone 1-146, from mouse

Synonyme(s) :

syntaxin 3, syntaxin 3A

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
1-146, monoclonal
Application:
immunohistochemistry
immunoprecipitation (IP)
western blot
Species reactivity:
human, rat
Citations:
11
Technique(s):
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
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Nom du produit

Anti-Syntaxin-3 Antibody, clone 1-146, clone 1-146, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

1-146, monoclonal

species reactivity

human, rat

species reactivity (predicted by homology)

mouse

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... STX3(6809)
rat ... Stx3(81802)

Analysis Note

Control
Rat brain tissue lysate
Evaluated by Western Blot in rat brain tissue lysate.
Western Blot Analysis: : 0.5 µg/mL dilution of this antibody detected Syntaxin-3 on 15 µg of rat brain tissue lysate.

Application

Detect Syntaxin-3 using this Anti-Syntaxin-3 Antibody, clone 1-146 validated for use in WB, IP, IH.
Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology

Biochem/physiol Actions

This antibody recognizes Syntaxin-3.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Approx. 33 kDa
Syntaxin-3, also known as Stx3, is a member of the SNARE family which are complexes involved in membrane fusion. Syntaxin-3 is expressed in epithelial cells and is found apically in MDCK and Caco-2 cells (1).

Immunogen

GST-tagged recombinant protein corresponding to residues contained within rat Syntaxin-3.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal in buffer containing 0.1 M Tris-glycine, pH 7.4, 150 mM NaCl with 0.05% NaN3.

Preparation Note

Maintain refrigerated at 2-8°C for 1 year from date of receipt.

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Classe de stockage

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Daniëlle Rianne José Verboogen et al.
eLife, 6 (2017-05-20)
SNARE proteins play a crucial role in intracellular trafficking by catalyzing membrane fusion, but assigning SNAREs to specific intracellular transport routes is challenging with current techniques. We developed a novel Förster resonance energy transfer-fluorescence lifetime imaging microscopy (FRET-FLIM)-based technique allowing
Adrian J Giovannone et al.
The Journal of biological chemistry, 293(15), 5478-5491 (2018-02-25)
Syntaxins are a conserved family of SNARE proteins and contain C-terminal transmembrane anchors required for their membrane fusion activity. Here we show that Stx3 (syntaxin 3) unexpectedly also functions as a nuclear regulator of gene expression. We found that alternative
Adrian J Giovannone et al.
Molecular biology of the cell, 28(21), 2843-2853 (2017-08-18)
Syntaxin 3 (Stx3), a SNARE protein located and functioning at the apical plasma membrane of epithelial cells, is required for epithelial polarity. A fraction of Stx3 is localized to late endosomes/lysosomes, although how it traffics there and its function in
Hiroshi Gomi et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 65(11), 637-653 (2017-09-16)
The comparative structure and expression of salivary components and vesicular transport proteins in the canine major salivary glands were investigated. Histochemical analysis revealed that the morphology of the five major salivary glands-parotid, submandibular, polystomatic sublingual, monostomatic sublingual, and zygomatic glands-was
Ritika Chatterjee et al.
Traffic (Copenhagen, Denmark), 24(7), 270-283 (2023-04-28)
Intracellular membrane fusion is mediated by membrane-bridging complexes of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). SNARE proteins are one of the key players in vesicular transport. Several reports shed light on intracellular bacteria modulating host SNARE machinery to establish

Numéro d'article de commerce international

RéférenceGTIN
MAB225804053252724909

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