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Merck

MAB4388

Mouse Anti-Stella Antibody

clone 3H5.2, Chemicon®, from mouse

Synonyme(s) :

Anti-Anti-Pgc7, Anti-Anti-STELLA

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
3H5.2, monoclonal
Application:
ELISA, ICC
Citations:
13

Principaux documents

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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

3H5.2, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunocytochemistry: suitable

input

sample type: human embryonic stem cell(s)
sample type induced pluripotent stem cell(s)
sample type: mouse embryonic stem cell(s)

isotype

IgG1

NCBI accession no.

NM_199286.2

UniProt accession no.

Q6W0C5

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

mouse ... Dppa3(73708)

General description

Stella is specifically expressed by oocytes, pluripotent cells and primordial germ cells at the time of their emergence in gastrulating embryos, and is an important maternal factor in the cleavage stages of mouse embryos (Bortvin, 2004). The requirement for stella in germ cell specification remains controversial, however, most embryos from stella deficient mice failed to develop normally and rarely reach the blastocyst stage (Bortvin, 2004; Payer, 2003). The stella gene encodes a protein with an SAP-like domain and splicing factor motif-like structure, suggesting possible roles in chromosomal organization and RNA processing (Payer, 2003).

Application

Mouse Anti-Stella Antibody detects level of Stella & has been published & validated for use in ELISA & IC.
Research Category
Stem Cell Research
Research Sub Category
Pluripotent & Early Differentiation

Biochem/physiol Actions

Reacts with stella from human and mouse.

Physical form

Format: Purified
Purified Immunoglobulin presented as a liquid in PBS with 0.1% sodium azide.

Preparation Note

Maintain refrigerated at 2-8C in undiluted aliquots for up to 12 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Classe de stockage

12 - Non Combustible Liquids

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Xun Xu et al.
Nature materials (2024-08-13)
Naive pluripotent stem cells have the highest developmental potential but their in vivo existence in the blastocyst is transient. Here we report a blastocyst motif substrate for the in vitro reversion of mouse and human pluripotent stem cells to a
Pengxiang Wang et al.
Cell proliferation, 57(1), e13533-e13533 (2023-08-04)
Primordial germ cells (PGCs) are the germline precursors that give rise to oocytes and sperm, ensuring the continuation of life. While the PGC specification is extensively studied, it remains elusive how the PGC population is sustained and expanded after they
Maurizio Zuccotti et al.
BMC developmental biology, 8, 97-97 (2008-10-08)
The maternal contribution of transcripts and proteins supplied to the zygote is crucial for the progression from a gametic to an embryonic control of preimplantation development. Here we compared the transcriptional profiles of two types of mouse MII oocytes, one
Wenlin Li et al.
Methods in molecular biology (Clifton, N.J.), 1074, 31-37 (2013-08-27)
The derivation of mouse embryonic stem cells (mESCs) from the inner cell mass (ICM) of mouse preimplantation blastocysts has provided tremendous opportunities in exploring mammalian development and pluripotent stem cell biology (Martin, Proc Natl Acad Sci U S A 78(12):7634-7638
Katja Linher et al.
PloS one, 4(12), e8263-e8263 (2009-12-17)
We have previously demonstrated that stem cells isolated from fetal porcine skin have the potential to form oocyte-like cells (OLCs) in vitro. However, primordial germ cells (PGCs), which must also be specified during the stem cell differentiation to give rise
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Contenu apparenté

Human Stem Cell Systems

As the focus of stem cell research undergoes a transition from animal to human models, researchers are in critical need of validated products to support the isolation, maintenance, differentiation, and characterization of human stem cells. While many reagents designed for rodent systems can be applied to human stem cell studies, they are not truly optimized for robust human stem cell culture or analysis. This is why human stem cell researchers have always trusted EMD Millipore, the first provider of commercially available human embryonic stem cells and human neural stem cell lines, to accelerate their research. All of our human stem cell systems are extensively tested in defined media culture, and differentiated progeny are comprehensively characterized with highly validated antibodies and detection reagents.

PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

Numéro d'article de commerce international

RéférenceGTIN
MAB438804053252579837

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