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Merck

MAB5504

Anti-Vesicular Glutamate Transporter 2 Antibody

clone 8G9.2, Chemicon®, from mouse

Synonyme(s) :

VGLUT2

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
8G9.2, monoclonal
Application:
IHC, WB
Citations:
123
Service technique
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

8G9.2, monoclonal

species reactivity

mouse, rat

species reactivity (predicted by homology)

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... SLC17A6(57084)

General description

Vesicular Glutamate Transporter 2 (VGLUT2) is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity.
56 kDa

Application

Detect Vesicular Glutamate Transporter 2 using this Anti-Vesicular Glutamate Transporter 2 Antibody validated for use in WB, IH.
Immunohistochemistry: A 1:50-1:300 dilution of a previous lot worked using ABC with NiDAB on floating mouse brain sections.

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts with VGLUT2 (Vesicular Glutamate Transporter 2).

Physical form

Format: Purified
Mouse monoclonal in PBS containing 0.1% sodium azide.

Analysis Note

Evaluated by Western Blot on Mouse brain lysates.

Western Blotting Analysis: 1:500 dilution of this antibody detected VGLUT2 on 10 µg of Mouse brain lysates.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


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Classe de stockage

10 - Combustible liquids

wgk

WGK 2



Certificats d'analyse (COA)

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Purkinje cell ataxin-1 modulates climbing fiber synaptic input in developing and adult mouse cerebellum.
Ebner, BA; Ingram, MA; Barnes, JA; Duvick, LA; Frisch, JL; Clark, HB; Zoghbi, HY; Ebner, TJ; Orr, HT
The Journal of Neuroscience null
I Pose et al.
Neuroscience, 172, 246-255 (2010-11-04)
The rostral ventro-medial medullary reticular formation is a complex structure that is involved with a variety of motor functions. It contains glycinergic neurons that are activated during active (rapid eye movement (REM)) sleep (AS); these neurons appear to be responsible
Peiyan Wong et al.
The Journal of comparative neurology, 510(4), 440-461 (2008-07-31)
The temporal cortex of grey squirrels contains three architectonically distinct regions. One of these regions, the temporal anterior (Ta) region has been identified in previous physiological and anatomical studies as containing several areas that are largely auditory in function. Consistent



Numéro d'article de commerce international

RéférenceGTIN
MAB550404053252397523