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Merck

MPTMAG-49K

MILLIPLEX® Mouse Pituitary Panel

Configurable Mouse Pituitary 7-Plex Panel

Synonyme(s) :

MPTMAG-49K product info, endocrine biomarker multiplex kit, mouse endocrine research tool, mouse growth and metabolism panel, mouse hormone assay overview, mouse pituitary hormone panel, multiplex hormone profiling kit, neuroendocrine marker panel mouse, pituitary function biomarker listing, reproductive biology product sheet

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A propos de cet article

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

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Nom du produit

MILLIPLEX® Mouse Pituitary Panel, Configurable Mouse Pituitary 7-Plex Panel

species reactivity

mouse

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

tissue/cellular lysate
serum
plasma
culture supernatant(s)

assay range

accuracy: 96-101%, standard curve range: 12.2-50,000 pg/mL
(TSH), standard curve range: 122-500,000 pg/mL
(Prolactin), standard curve range: 2.4-10,000 pg/mL
(ACTH), standard curve range: 2.4-10,000 pg/mL
(BDNF), standard curve range: 24.4-100,000 pg/mL
(FSH), standard curve range: 4.9-20,000 pg/mL
(GH), standard curve range: 4.9-20,000 pg/mL
(LH), inter-assay cv: <20%
intra-assay cv: <15%

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Catégories apparentées

General description

The pituitary gland, often referred to as the “master gland,” regulates multiple endocrine functions through the secretion of key hormones. This panel—ACTH, BDNF, FSH, GH, LH, Prolactin, and TSH—captures essential indicators of adrenal, thyroid, gonadal, and neuroendocrine activity. The MILLIPLEX® Mouse Pituitary Panel enables multiplexed quantification of these biomarkers in mouse serum or plasma, supporting research in reproductive biology, metabolism, and endocrine disorders.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in mouse serum, plasma, or cell/tissue culture supernatants.

Analytes Included: ACTH, BDNF, FSH, GH, LH, Prolactin, TSH

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:

  • Targets key pituitary hormones involved in endocrine and neuroendocrine regulation
  • Includes 7 analytes relevant to metabolism, growth, reproduction, and neuronal function
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with mouse serum, plasma, and cell/tissue culture supernatants
  • Designed for research in reproductive biology, endocrine disorders, and neuroendocrine signaling
Benefits:

  • Provides a comprehensive profile of pituitary hormone biomarkers in mouse models
  • Supports investigation of endocrine function and hormonal regulation mechanisms
  • Facilitates evaluation of therapeutic interventions and endocrine toxicity
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for preclinical and translational research

Legal Information

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Thomas Blum et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(30), 15236-15243 (2019-07-10)
Dopamine neurons of the hypothalamic arcuate nucleus (ARC) tonically inhibit the release of the protein hormone prolactin from lactotropic cells in the anterior pituitary gland and thus play a central role in prolactin homeostasis of the body. Prolactin, in turn
Tomohiro Terasaka et al.
Endocrinology, 160(8), 1999-2014 (2019-06-13)
Gonadotropin secretion, which is elicited by GnRH stimulation of the anterior pituitary gonadotropes, is a critical feature of reproductive control and the maintenance of fertility. In addition, activation of the GnRH receptor (GnRHR) regulates transcription and translation of multiple factors
Marina O Fernandez et al.
Endocrinology, 158(1), 121-133 (2016-11-15)
The peroxisome-proliferator activated receptor γ (PPARγ) is expressed in the hypothalamus in areas involved in energy homeostasis and glucose metabolism. In this study, we created a deletion of PPARγ brain-knockout (BKO) in mature neurons in female mice to investigate its
Amanda Rodriguez et al.
Development (Cambridge, England), 146(23) (2019-11-11)
The number and quality of oocytes within the ovarian reserve largely determines fertility and reproductive lifespan in mammals. An oocyte-specific transcription factor cascade controls oocyte development, and some of these transcription factors, such as newborn ovary homeobox gene (NOBOX), are
Karen J Tonsfeldt et al.
Journal of the Endocrine Society, 3(4), 716-733 (2019-03-25)
In rodents, the preovulatory LH surge is temporally gated, but the timing cue is unknown. Estrogen primes neurons in the anteroventral periventricular nucleus (AVPV) to secrete kisspeptin, which potently activates GnRH neurons to release GnRH, eliciting a surge of LH
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Numéro d'article de commerce international

RéférenceGTIN
MPTMAG-49K-0304053252829222
MPTMAG-49K-0704053252829055
MPTMAG-49K-0504053252829031
MPTMAG-49K-0104053252829208
MPTMAG-49K-0604053252829048
MPTMAG-49K-0204053252829215
MPTMAG-49K-0404053252829024

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