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Merck

ST1042

Anti-PKD2 Rabbit pAb

liquid, Calbiochem®

Synonyme(s) :

Anti-Protein Kinase D2

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A propos de cet article

NACRES:
NA.41
UNSPSC Code:
12352203

Principaux documents

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Nom du produit

Anti-PKD2 Rabbit pAb, liquid, Calbiochem®

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

dilution

(Immunoblotting (1:500-1:5000)
Immunoprecipitation (1-4 µg/mg lysate))

isotype

IgG

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... PKD2(5311)

Analysis Note

Positive Control
HEK 293 cells

Application


Immunoblotting (1:500-1:5000)
Immunoprecipitation (1-4 g/mg lysate)

Disclaimer

Toxicity: Highly Toxic (H)

General description

Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~105 kDa PKD2 protein.
Recognizes the ~105 kDa PKD2 protein in HEK293 cells.
This Anti-PKD2 Rabbit pAb is validated for use in Immunoblotting, Immunoprecipitation for the detection of PKD2.

Immunogen

Human
a synthetic peptide corresponding to amino acids near the C-terminus of human PKD2

Other Notes

Rey, O., et al. 2003. Biochem. Biophys. Res. Commun.302, 817.
Sturany, S., et al. 2002. J. Biol. Chem.277, 29431.
Sturany, S., et al. 2001. J. Biol. Chem.276, 3310.
This antibody does not cross-react with PKD1 or PKD3. Antibody should be titrated for optimal use in individual systems.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In PBS.

Preparation Note

Following initial use, aliquot and freeze (-20°C) for long-term storage. Avoid freeze/thaw.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Classe de stockage

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Clara Aicart-Ramos et al.
The Journal of biological chemistry, 291(45), 23516-23531 (2016-09-25)
Protein kinase D (PKD) isoforms are protein kinase C effectors in signaling pathways regulated by diacylglycerol. Important physiological processes (including secretion, immune responses, motility, and transcription) are placed under diacylglycerol control by the distinctive substrate specificity and subcellular distribution of
Jianfen Guo et al.
The Journal of biological chemistry, 286(8), 6500-6509 (2010-12-16)
Protein kinase D (PKD) exists as a family of structurally related enzymes that are activated through similar phosphorylation-dependent mechanisms involving protein kinase C (PKC). While individual PKD isoforms could in theory mediate distinct biological functions, previous studies identify a high
Tim Eiseler et al.
The Journal of biological chemistry, 291(1), 462-477 (2015-10-29)
Vesicle formation and fission are tightly regulated at the trans-Golgi network (TGN) during constitutive secretion. Two major protein families regulate these processes: members of the adenosyl-ribosylation factor family of small G-proteins (ARFs) and the protein kinase D (PKD) family of
Milena Armacki et al.
Gastroenterology, 159(3), 1019-1035 (2020-05-25)
Pancreatic tumor cells release small extracellular vesicles (sEVs, exosomes) that contain lipids and proteins, RNA, and DNA molecules that might promote formation of metastases. It is not clear what cargo these vesicles contain and how they are released. Protein kinase
Christoph Wille et al.
Journal of leukocyte biology, 104(3), 615-630 (2018-04-16)
Neutrophils are important mediators of the innate immune defense and of the host response to a physical trauma. Because aberrant infiltration of injured sites by neutrophils was shown to cause adverse effects after trauma, we investigated how neutrophil infiltration could

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