00895
Dextran
analytical standard, 410,000
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A propos de cet article
Formule linéaire :
[C6H10O5]n
Numéro CAS:
NACRES:
NA.24
UNSPSC Code:
12352201
EC Number:
232-677-5
MDL number:
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Laissez-nous vous aiderInChI key
FZWBNHMXJMCXLU-UHFFFAOYSA-N
InChI
1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
grade
analytical standard
form
powder or crystals
analyte chemical class(es)
oligosaccharides
Quality Level
technique(s)
gel permeation chromatography (GPC): suitable
Mw/Mn
~1.73
application(s)
food and beverages
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General description
Dextran (mol. wt. 410,000) belongs to the family of neutral polysaccharides, which are recognized as contaminants in sugar processing and other food production industries. These are composed of chains of D-glucose units connected by alpha-(1-6) linkages of varying lengths. They are found as bacterial extracellular polysaccharides and reportedly synthesized from sucrose by beneficial lactic acid bacteria, such as Leuconostoc mesenteroides and Lactobacillus brevis. They are incorporated in bakery products to improve the crumb texture, softness, and loaf volume, as stabilizers and additives in confectionery, flavor extract, icing compositions, beverages including soft drinks, milk, etc.
Application
- Dextran in Drug Delivery: A study in "Journal of Biomedical Materials Research Part A" demonstrated how dextran, a biopolymer, enhances wound healing. It focused on collagen-polyurethane-dextran hydrogels, which inhibit inflammation and promote collagen fibrillogenesis, making dextran crucial for tissue engineering and medical applications (Aguayo-Morales et al., 2024).
- Dextran as a Blood Plasma Expander: Research in "Redox Biology" highlighted the role of dextran in reducing systemic iron overload stress. This study provides insights into how dextran′s properties are beneficial for managing conditions like anemia and other blood volume deficiencies (Zhao et al., 2024).
- Dextran in Cell Culture: An article in ""International Journal of Biological Macromolecules"" explored the use of dextran-based antibacterial hydrogels. These gels are used for fluorescent sensors in bioanalytical applications, showing dextran′s utility in cell culture and microbial monitoring (Bai et al., 2024).
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Classe de stockage
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Functional polymers based on dextran
Polysaccharide-based Fibers and Composites: Chemical and Engineering Fundamentals and Industrial Applications, 199-291 (2006)
Dextran?the polysaccharide with versatile uses
Bhavani LA and Nisha J
International Journal of Pharmacy and Biological Sciences, 1(4), 569-573 (2010)
Dmitri Simberg et al.
Biomaterials, 30(23-24), 3926-3933 (2009-04-28)
In order to understand the role of plasma proteins in the rapid liver clearance of dextran-coated superparamagnetic iron oxide (SPIO) in vivo, we analyzed the full repertoire of SPIO-binding blood proteins using novel two-dimensional differential mass spectrometry approach. The identified
Michael J Pitman et al.
The Annals of otology, rhinology, and laryngology, 122(4), 283-287 (2013-05-24)
We investigated the quantity of recurrent laryngeal nerve motoneurons (RLNMs) that survive after transection and anastomosis of the rat recurrent laryngeal nerve (RLN), as well as the impact of the anastomosis site on RLN regeneration. Ten rats underwent right RLN
Elizabeth M Bradshaw et al.
Nature neuroscience, 16(7), 848-850 (2013-05-28)
In our functional dissection of the CD33 Alzheimer's disease susceptibility locus, we found that the rs3865444(C) risk allele was associated with greater cell surface expression of CD33 in the monocytes (t50 = 10.06, P(joint) = 1.3 × 10(-13)) of young
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