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Merck

49159

D-(+)-Glucose monohydrate

suitable for microbiology, ≥99.0%

Synonyme(s) :

Dextrose monohydrate, Glucose

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A propos de cet article

Formule empirique (notation de Hill) :
C6H12O6 · H2O
Numéro CAS:
14431-43-7
Poids moléculaire :
198.17
UNSPSC Code:
41106212
NACRES:
NA.85
PubChem Substance ID:
329757440
EC Number:
218-914-5
Beilstein/REAXYS Number:
5250278
MDL number:
MFCD00149450

Principaux documents

Voir toute la documentation
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Nom du produit

D-(+)-Glucose monohydrate, suitable for microbiology, ≥99.0%

InChI key

SPFMQWBKVUQXJV-BTVCFUMJSA-N

InChI

1S/C6H12O6.H2O/c7-1-3(9)5(11)6(12)4(10)2-8;/h1,3-6,8-12H,2H2;1H2/t3-,4+,5+,6+;/m0./s1

SMILES string

O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O

assay

≥99.0% (sum of enantiomers, HPLC)
≥99.0%

form

powder

optical activity

[α]20/D +49±3°, 3 hr, c = 10% in H2O

shelf life

limited shelf life, expiry date on the label

packaging

pkg of 1 kg
pkg of 5 kg

storage condition

(Tightly closed)

ign. residue

≤0.1% (as SO4)

pH

6-7 (20 °C, 100 g/L in water)

solubility

H2O: 0.1 g/mL, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

As: ≤0.1 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

application(s)

microbiology

Quality Level

200

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Catégories apparentées

Application

D-(+)-Glucose monohydrate is commonly used as an ingredient in many microbial culture media for the growth and identification of bacteria, yeasts, and molds from various pharmaceutical, environmental, and food and beverage samples.

General description

D-(+)-Glucose monohydrate, commonly known as glucose or dextrose, has several microbiological applications. It is used as a carbon source in microbial culture media to promote the growth and propagation of variety of microorganisms. Glucose is a simple sugar and a primary energy source for bacterial cell metabolism. Glucose monohydrate can also be used as a supplement in media to enhance the growth and productivity of microorganisms used in fermentation processes, for example, in the production of antibiotics, organic acids, and enzymes. It plays an important role in diauxic growth, which refers to the phenomenon in which bacterial cells preferentially utilize glucose as a carbon source before switching to other energy sources. In addition, glucose is a common component in numerous selective and differential media formulations used in the identification and characterization of microorganisms.

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
BCCN8208
BCCN1192
BCCL9749
BCCL0892
BCCK5816

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Consulter la Bibliothèque de documents

Cicera R Lazzarotto et al.
Nature protocols, 13(11), 2615-2642 (2018-10-21)
Circularization for in vitro reporting of cleavage effects by sequencing (CIRCLE-seq) is a sensitive and unbiased method for defining the genome-wide activity (on-target and off-target) of CRISPR-Cas9 nucleases by selective sequencing of nuclease-cleaved genomic DNA (gDNA). Here, we describe a
Antonio Marsella et al.
Cell reports, 34(13), 108906-108906 (2021-04-01)
The Mre11-Rad50-Xrs2 (MRX) complex detects and processes DNA double-strand breaks (DSBs). Its DNA binding and processing activities are regulated by transitions between an ATP-bound state and a post-hydrolysis cutting state that is nucleolytically active. Mre11 endonuclease activity is stimulated by
Daphne H E W Huberts et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(32), 11727-11731 (2014-07-30)
Calorie restriction (CR) is often described as the most robust manner to extend lifespan in a large variety of organisms. Hence, considerable research effort is directed toward understanding the mechanisms underlying CR, especially in the yeast Saccharomyces cerevisiae. However, the
Paola Rusmini et al.
Autophagy, 15(4), 631-651 (2018-10-20)
Macroautophagy/autophagy, a defense mechanism against aberrant stresses, in neurons counteracts aggregate-prone misfolded protein toxicity. Autophagy induction might be beneficial in neurodegenerative diseases (NDs). The natural compound trehalose promotes autophagy via TFEB (transcription factor EB), ameliorating disease phenotype in multiple ND
Maiken Mellergaard et al.
The Journal of biological chemistry, 295(33), 11803-11821 (2020-07-02)
Staphylococcus aureus is among the leading causes of bacterial infections worldwide. The pathogenicity and establishment of S. aureus infections are tightly linked to its ability to modulate host immunity. Persistent infections are often associated with mutant staphylococcal strains that have
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