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Merck

D172405

N,N-Dimethyl-4-nitrosoaniline

97%, powder or chunks

Synonyme(s) :

4-Nitroso-N,N-dimethylaniline

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A propos de cet article

Formule linéaire :
ONC6H4N(CH3)2
Numéro CAS:
Poids moléculaire :
150.18
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
205-343-1
MDL number:
Beilstein/REAXYS Number:
607293
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Nom du produit

N,N-Dimethyl-4-nitrosoaniline, ≥97%

Quality Level

assay

≥97%

form

powder or chunks

mp

85-87 °C (lit.)

solubility

ethanol: 5% (green to very dark green)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CN(C)c1ccc(cc1)N=O

InChI

1S/C8H10N2O/c1-10(2)8-5-3-7(9-11)4-6-8/h3-6H,1-2H3

InChI key

CMEWLCATCRTSGF-UHFFFAOYSA-N

Application

N,N-Dimethyl-4-nitrosoaniline has been used along with imidazole to detect the formation of singlet oxygen in cells.

Biochem/physiol Actions

N,N-Dimethyl-4-nitrosoaniline is used for the detection of singlet oxygen. Singlet oxygen reacts with imidazole and thereby bleaches N,N-Dimethyl-4-nitrosoaniline via oxidation. Bleaching of N,N-Dimethyl-4-nitrosoaniline is observed as reduction in the absorption at 438nm.


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Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Self-heat. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Classe de stockage

4.2 - Pyrophoric and self-heating hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Elif Pehlivanoglu-Mantas et al.
Water research, 40(6), 1287-1293 (2006-03-01)
To assess the stability of precursors of the chloramine disinfection byproduct N-nitrosodimethylamine (NDMA) under conditions expected in effluent-dominated surface waters, effluent samples from four municipal wastewater treatment plants were subjected to chlorination and chloramination followed by incubation in the presence
Zhuo Chen et al.
Environmental science & technology, 40(23), 7290-7297 (2006-12-22)
This paper presents mechanistic studies on the formation of NDMA, a newly identified chloramination disinfection byproduct, from reactions of monochloramine with natural organic matter. A kinetic model was developed to validate proposed reactions and to predict NDMA formation in chloraminated
Abdullah Shafique Ahmad et al.
Toxicological sciences : an official journal of the Society of Toxicology, 89(1), 265-270 (2005-10-21)
The clinical side effects associated with the inhibition of cyclooxygenase enzymes under pathologic conditions have recently raised concerns. A better understanding of neuroinflammatory mechanisms and neuronal survival requires knowledge of cyclooxygenase downstream pathways, especially PGE2 and its G-protein-coupled receptors. In