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A propos de cet article
Formule linéaire :
ONC6H4N(CH3)2
Numéro CAS:
Poids moléculaire :
150.18
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
205-343-1
MDL number:
Beilstein/REAXYS Number:
607293
Service technique
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Laissez-nous vous aiderNom du produit
N,N-Dimethyl-4-nitrosoaniline, ≥97%
Quality Level
assay
≥97%
form
powder or chunks
mp
85-87 °C (lit.)
solubility
ethanol: 5% (green to very dark green)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
CN(C)c1ccc(cc1)N=O
InChI
1S/C8H10N2O/c1-10(2)8-5-3-7(9-11)4-6-8/h3-6H,1-2H3
InChI key
CMEWLCATCRTSGF-UHFFFAOYSA-N
Application
N,N-Dimethyl-4-nitrosoaniline has been used along with imidazole to detect the formation of singlet oxygen in cells.
Biochem/physiol Actions
N,N-Dimethyl-4-nitrosoaniline is used for the detection of singlet oxygen. Singlet oxygen reacts with imidazole and thereby bleaches N,N-Dimethyl-4-nitrosoaniline via oxidation. Bleaching of N,N-Dimethyl-4-nitrosoaniline is observed as reduction in the absorption at 438nm.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Self-heat. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Classe de stockage
4.2 - Pyrophoric and self-heating hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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The clinical side effects associated with the inhibition of cyclooxygenase enzymes under pathologic conditions have recently raised concerns. A better understanding of neuroinflammatory mechanisms and neuronal survival requires knowledge of cyclooxygenase downstream pathways, especially PGE2 and its G-protein-coupled receptors. In

