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Merck

E6133

Ethanolamine hydrochloride

≥99.0%

Synonyme(s) :

mea hydrochloride, monoethanolamine hydrochloride, 2-Aminoethanol hydrochloride

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A propos de cet article

Formule linéaire :
H2NCH2CH2OH · HCl
Numéro CAS:
2002-24-6
Poids moléculaire :
97.54
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
57654165
EC Number:
217-900-6
Beilstein/REAXYS Number:
3542892
MDL number:
MFCD00012892

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Nom du produit

Ethanolamine hydrochloride, ≥99.0%

InChI key

PMUNIMVZCACZBB-UHFFFAOYSA-N

InChI

1S/C2H7NO.ClH/c3-1-2-4;/h4H,1-3H2;1H

SMILES string

NCCO.[H]Cl

assay

≥99.0%

form

powder or crystals

storage condition

dry at room temperature

technique(s)

HPLC: suitable

color

white

pH

9—10

pKa (25 °C)

9.5

mp

82-84 °C (lit.)

solubility

water: 0.33 g/mL, clear, colorless to very faintly yellow

density

1.07 g/cm3 at 20—25 °C
1.12 g/cm3 at 20—25 °C

suitability

suitable for chromatography

application(s)

general analytical
life science and biopharma
pharmaceutical

Quality Level

300

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Catégories apparentées

Application

Ethanolamine hydrochloride has been used:
  • in overnight incubation of the tips to attach primary amine groups at the tip surface
  • in the preparation of DMEM (dulbecco′s modified eagle′s medium)/F-12 media to culture human epidermal growth factor receptor 2 (HER2) cells derived from MMTV-HER2 transgenic mouse mammary tumors
  • to administer the cultures to study its effect on the endogenous phosphatidyl ethanolamine pool and autophagy process
  • in a study as a reagent to study molecular interactions and adhesion forces in biological systems using Atomic Force Microscopy
  • to prepare the reagent for surface-enhanced laser desorption ionization analysis, aimed at studying the role of Interleukins

Biochem/physiol Actions

Ethanolamine hydrochloride is utilized as a carbon and nitrogen source by bacteria that differs phylogenetically. It exists as phosphotidylethanolamine in the bacterial and mammalian cell membrane. Ethanolamine-ammonia lyase is responsible for the degradation of ethanolamine into acetaldehyde and ammonia. Ethanolamine is known to positively support lipid accumulation in photosynthetic organism model.

Features and Benefits

  • Suitable for Immunology, Cellular Biology and Biochemical Research
  • Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
  • Effective Buffering Agent with a pKa of 9.5 (25 °C)

General description

Ethanolamine hydrochloride, a versatile compound in biochemistry and molecular biology, plays a pivotal role in diverse research areas. Primarily, it functions as a buffering agent, ensuring a stable pH environment crucial for enzymatic reactions, protein solubilization, and other biological processes. Its significance extends to membrane protein studies, aiding in the extraction of these proteins from cell membranes. It also finds utility in cell culture and as a reagent for biological sample preparation, simplifying nucleic acid and protein isolation, as well as facilitating the detection of proteins by western blotting and immunohistochemistry. This compound′s wide-ranging applications make it indispensable in biochemical research, contributing to various experimental procedures and advancing our understanding in fields such as molecular biology, immunology, and cellular biology.

Other Notes

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
SHBT5326
SHBT4368
SHBT3467
SHBT5327
SHBT5008

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Consulter la Bibliothèque de documents

The role of interleukin-6 (IL-6) in human sulfur mustard (HD) toxicology
Arroyo C M, et al.
International Journal of Toxicology, 20, 281-296 (2001)
Foodborne Diseases: New Insights for the Healthcare Professional, 14-14 (2012)
Amino Alcohols-Advances in Research and Application, 29-29 (2013)
Selective cyclin-dependent kinase 2/cyclin A antagonists that differ from ATP site inhibitors block tumor growth
Mendoza N, et al.
Cancer Research, 63(5), 1020-1024 (2003)
Unbinding molecular recognition force maps of localized single receptor molecules by atomic force microscopy
Sotres J, et al.
ChemPhysChem, 9(4), 590-599 (2008)
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