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N1511

β-Nicotinamide-adénine-dinucléotide hydrate

greener alternative

≥99%

Synonyme(s) :

β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucléotide, NAD, Nadide

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A propos de cet article

Formule empirique (notation de Hill) :
C21H27N7O14P2 · xH2O
Numéro CAS:
53-84-9
Poids moléculaire :
663.43 (anhydrous basis)
PubChem Substance ID:
24897495
eCl@ss:
39200202
UNSPSC Code:
41106305
NACRES:
NA.55
EC Number:
200-184-4
MDL number:
MFCD00036253
Assay:
≥99%
Biological source:
Saccharomyces cerevisiae
Form:
crystalline powder
Storage temp.:
−20°C
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biological source

Saccharomyces cerevisiae

Quality Level

200

assay

≥99%

form

crystalline powder

greener alternative product characteristics

Waste Prevention
Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

color

white to off-white

greener alternative category

DfS-Developed

storage temp.

−20°C

SMILES string

NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChI key

BAWFJGJZGIEFAR-NNYOXOHSSA-N

Gene Information

human ... ESR1(2099), ESR2(2100)

General description

We are committed to bringing you Greener Alternative Products that adhere to one or more of the 12 Principles of Green Chemistry. Beta-Nicotinamide adenine dinucleotide is a bio-derived redox cofactor that works together with enzymes as part of a biocatalyst system. It can be efficiently recycled in many reactions, enabling selective oxidations while reducing waste and supporting greener, more sustainable chemical processes. Click here for more information.

Application

β-Nicotinamide adenine dinucleotide hydrate has been used:
  • to prepare NAD+ standard solution for a study on NAD+ metabolomics
  • as a component of MurI assay reaction partial mixture for glutamate racemase reaction
  • as a component of a chromogenic staining solution to stain zebrafish embryos

Biochem/physiol Actions

β-Nicotinamide adenine dinucleotide (β-NAD) is a cofactor of alcohol dehydrogenase and acts as an inhibitory neurotransmitter in visceral smooth muscles. The NAD/NADH ratio has a role in the regulation of intracellular redox potential. It thereby influences metabolic reactions in vivo.
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Packaging

Produit conditionné en fonction du poids solide.

Other Notes

Il s′agit de la forme courante du NAD.
Crystalline NAD contains less than 0.1% (w/w) residual organic solvent, is less hygroscopic and electrostatic, and is more stable at ambient temperature than amorphous NAD.

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Classe de stockage

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
0000560106
0000544967
0000560106
0000544967
0000520679

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Consulter la Bibliothèque de documents

beta-Nicotinamide adenine dinucleotide is an inhibitory neurotransmitter in visceral smooth muscle
Mutafova-Yambolieva VN, et al.
Proceedings of the National Academy of Sciences of the USA (2007)
Determination of the cytosolic NADPH/NADP ratio in Saccharomyces cerevisiae using shikimate dehydrogenase as sensor reaction
Zhang J, et al.
Scientific Reports (2015)
The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development
Kroeger Jr PT, et al.
Developmental Biology (2017)
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