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A propos de cet article
Formule empirique (notation de Hill) :
C8H11NO3 · HCl
Numéro CAS:
Poids moléculaire :
205.64
NACRES:
NA.55
PubChem Substance ID:
eCl@ss:
34058008
UNSPSC Code:
12352205
EC Number:
200-386-2
MDL number:
Beilstein/REAXYS Number:
3632435
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≥98% (HPLC)
form
powder
technique(s)
HPLC: suitable
color
white to off-white
mp
214-215 °C (lit.)
SMILES string
Cl[H].Cc1ncc(CO)c(CO)c1O
InChI
1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
InChI key
ZUFQODAHGAHPFQ-UHFFFAOYSA-N
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Application
Pyridoxine hydrochloride has been used:
- as a vitamin supplement in the basal medium for the cultivation of Bacillus mojavensis and Bacillus subtilis strains
- as a supplement in pre-conditioning medium/MS salts to initiate somatic embryogenesis induction of Coffea canephora seeds
- for oral administration in piglets to study its effect on the development of homocysteinemia
Biochem/physiol Actions
Pyridoxine/Vitamin B6 plays a key role in the nervous, immune, and endocrine systems. It is also involved in the metabolic processes of proteins, lipids, and carbohydrates. Deficiency of pyridoxine may lead to convulsions and epileptic encephalopathy and result in infant abnormalities.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
Classe de stockage
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Marie-Édith Côté-Robitaille et al.
Journal of nutritional science, 4, e31-e31 (2015-10-27)
Homocysteine (Hcy) is an intermediary sulphur amino acid recognised for pro-oxidative properties in several species which may weaken immune competence in piglets. In this species, there is an acute 10-fold increase of concentrations of plasma Hcy (pHcy) during the first
Vijay P Singh et al.
The Journal of organic chemistry, 78(4), 1478-1487 (2013-01-16)
Vitamin B6 is involved in a variety of enzymatic transformations. Some recent findings also indicate an antioxidant role of the vitamin in biological systems. We set out to turn pyridoxine (1a) into a catalytic chain-breaking and hydroperoxide-decomposing antioxidant by replacing
Manfred Eggersdorfer et al.
Angewandte Chemie (International ed. in English), 51(52), 12960-12990 (2012-12-05)
The discovery of vitamins as essential factors in the diet was a scientific breakthrough that changed the world. Diseases such as scurvy, rickets, beriberi, and pellagra were recognized to be curable with an adequate diet. These diseases had been prevalent
Paniz Izadi et al.
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The formation of combined electrogenic/electrotrophic biofilms from marine sediments for the development of microbial energy storage systems was studied. Sediment samples from the German coasts of the Baltic and the North Sea were used as inocula for biofilm formation. Anodic
Barbara Plecko et al.
Neurology, 82(16), 1425-1433 (2014-03-25)
To determine whether patients with pyridoxine-responsive seizures but normal biomarkers for antiquitin deficiency and normal sequencing of the ALDH7A1 gene may have PNPO mutations. We sequenced the PNPO gene in 31 patients who fulfilled the above-mentioned criteria. We were able
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