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Merck

PHR1312

o-xylène

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

1,2-diméthylbenzène

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A propos de cet article

Formule linéaire :
C6H4(CH3)2
Numéro CAS:
95-47-6
Poids moléculaire :
106.17
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823298
EC Number:
202-422-2
Beilstein/REAXYS Number:
1815558
MDL number:
MFCD00008519

Principaux documents

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InChI

1S/C8H10/c1-7-5-3-4-6-8(7)2/h3-6H,1-2H3

SMILES string

Cc1ccccc1C

InChI key

CTQNGGLPUBDAKN-UHFFFAOYSA-N

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to NIST 3003, traceable to USP 1601849

vapor density

3.7 (vs air)

vapor pressure

<0.1 atm ( 21.1 °C), 16 mmHg ( 37.7 °C), 7 mmHg ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

867 °F

expl. lim.

7 %

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

300

refractive index

n20/D 1.505 (lit.)

bp

143-145 °C (lit.)

mp

-26--23 °C (lit.)

density

0.879 g/mL at 20 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

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Catégories apparentées

General description

o-Xylene is a nonoxygenated, homocyclic aromatic compound that occurs as a constituent of petroleum. It belongs to the class of volatile organic compounds (VOCs) having vapor pressure high enough to vaporize under normal conditions and enter into the atmosphere. It is found to be relatively water-soluble and suspected to have carcinogenic properties.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB8972 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Asp. Tox. 1 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Classe de stockage

3 - Flammable liquids

wgk

WGK 2

flash_point_f

89.6 °F - closed cup

flash_point_c

32.0 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Anaerobic degradation of toluene and o-xylene by a methanogenic consortium.
Edwards EA and Grbic-Galic D
Applied and Environmental Microbiology, 60(1), 313-322 (1994)
Separation and determination of benzene, toluene, ethylbenzene and o-xylene compounds in water using directly suspended droplet microextraction coupled with gas chromatography-flame ionization detector.
Sarafraz-Yazdi, et al.
Talanta, 78(3), 936-941 (2009)
Maia Chanrion et al.
Nature communications, 5, 5005-5005 (2014-10-09)
Epithelial-to-mesenchymal transition-like (EMT-like) is a critical process allowing initiation of metastases during tumour progression. Here, to investigate its role in intestinal cancer, we combine computational network-based and experimental approaches to create a mouse model with high metastatic potential. Construction and
Casper Bindzus Foldager et al.
Cartilage, 5(2), 123-132 (2014-04-01)
The objective of the present study was to investigate the presence and distribution of 2 basement membrane (BM) molecules, laminin and collagen type IV, in healthy and degenerative cartilage tissues. Normal and degenerated tissues were obtained from goats and humans
Pawaree Saisawat et al.
Kidney international, 85(6), 1310-1317 (2013-10-25)
Congenital abnormalities of the kidney and urinary tract (CAKUT) account for approximately half of children with chronic kidney disease and they are the most frequent cause of end-stage renal disease in children in the US. However, its genetic etiology remains
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