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Merck

PHR1351

myo-inositol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

1,2,3,4,5,6-hexahydroxycyclohexane, i-inositol, méso-inositol

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A propos de cet article

Formule empirique (notation de Hill) :
C6H12O6
Numéro CAS:
Poids moléculaire :
180.16
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
201-781-2
Beilstein/REAXYS Number:
1907329
MDL number:
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InChI key

CDAISMWEOUEBRE-GPIVLXJGSA-N

InChI

1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H/t1-,2-,3-,4+,5-,6-

SMILES string

O[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0000485, traceable to USP 1340960

vapor density

6.2 (vs air)

API family

inositol

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

mp

222-227 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

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General description

Inositol is a structural isomer of glucose and a sugar alcohol. It is known to be a remedy for mild depression and neurasthenia.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Constituant des phospholipides membranaires, ancres glycosylphosphatidylinositol qui accrochent des glycoprotéines à la surface des cellules, et seconds messagers inositol-phosphate.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3650 in the slot below. This is an example certificate only and may not be the lot that you receive.
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Classe de stockage

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Natural medications for psychiatric disorders : considering the alternatives (2008)
Dietmar Weichert et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(29), 10744-10748 (2014-07-10)
Structural studies on G protein-coupled receptors (GPCRs) provide important insights into the architecture and function of these important drug targets. However, the crystallization of GPCRs in active states is particularly challenging, requiring the formation of stable and conformationally homogeneous ligand-receptor
Sookhee Bang et al.
Molecular endocrinology (Baltimore, Md.), 28(7), 1186-1193 (2014-06-01)
Metformin is a biguanide drug that is widely prescribed for type 2 diabetes. Metformin suppresses hepatic gluconeogenesis and increases fatty acid oxidation. Although studies have suggested that metformin acts, at least in part, via activation of the liver kinase B1
Dora Lippai et al.
Alcoholism, clinical and experimental research, 38(8), 2217-2224 (2014-08-27)
Chronic alcohol impairs gut barrier function and induces inflammatory cytokines. The effects of acute alcohol binge on the gut are partially understood. Micro-RNA-155 (miR-155), a modulator of cytokine and T-cell immune response in the gut, stabilizes tumor necrosis factor-α (TNFα)
Leonard C Edelstein et al.
Blood, 124(23), 3450-3458 (2014-10-09)
Human platelets express 2 thrombin receptors: protease-activated receptor (PAR)-1 and PAR4. Recently, we reported 3.7-fold increased PAR4-mediated aggregation kinetics in platelets from black subjects compared with white subjects. We now show that platelets from blacks (n = 70) express 14%

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