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Merck

27109

Acide citrique

meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance)

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A propos de cet article

Formule linéaire :
HOC(COOH)(CH2COOH)2
Numéro CAS:
77-92-9
Poids moléculaire :
192.12
NACRES:
NA.21
PubChem Substance ID:
329752978
eCl@ss:
39021801
UNSPSC Code:
12352106
EC Number:
201-069-1
MDL number:
MFCD00011669
Beilstein/REAXYS Number:
782061
Assay:
99.5-100.5% (based on anhydrous substance)
Form:
grit

Principaux documents

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Quality Level

200

assay

99.5-100.5% (based on anhydrous substance)

form

grit

quality

anhydrous, meets analytical specification of Ph. Eur., BP, USP, E330

expl. lim.

8 %, 65 °F

impurities

residual solvents, complies, ≤0.0005% heavy metals (as Pb), ≤0.5% water (Karl Fischer)

ign. residue

≤0.05% (as SO4)

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

mp

153-159 °C (lit.)

solubility

water: 383 g/L at 25 °C

anion traces

chloride (Cl-): ≤50 ppm, oxalate (as oxalic acid): ≤100 ppm, sulfate (SO42-): ≤100 ppm

cation traces

As: ≤1 ppm, Ca: ≤200 ppm, Cu: ≤10 ppm, Fe: ≤10 ppm, Hg: ≤1 ppm, Pb: ≤0.5 ppm, Zn: ≤10 ppm

suitability

complies for appearance of solution, complies for reaction against H2SO4

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O

InChI

1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

KRKNYBCHXYNGOX-UHFFFAOYSA-N

Gene Information

human ... SRC(6714)

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Catégories apparentées

Application

Citric acid was used as a test reagent for studying whether the novel pyridazinylpiperazine analog TPRV-1 inhibitor can reduce cough reflex induced by citric acid and capsaicin in guinea pig.

Biochem/physiol Actions

Citric acid in dietary form can augments absorption of aluminium in antacids. It also facilitates the phytoremediation of heavy metal contaminated soil and can transform cadmium into more transportable forms.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319,H335

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Classe de stockage

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
SDBB5508
STBK6636
STBK6336
SDBB1594
SDBB0858

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Consulter la Bibliothèque de documents

P Slanina et al.
Clinical chemistry, 32(3), 539-541 (1986-03-01)
Ten healthy men ingested, twice daily between meals, during each of the seven-day experimental periods: (a) citric acid (as lemon juice), (b) Al(OH)3, or (c) Al(OH)3 + citric acid. Whole blood sampled after each dietary period was analyzed electrothermally after
Y X Chen et al.
Chemosphere, 50(6), 807-811 (2003-04-12)
Adsorption and hydroponics experiments were conducted to study the role of citric acid on the phytoremediation of heavy metal contaminated soil. The results show that addition of citric acid decreased the adsorption of both lead and cadmium, such an effect
Sum Yee Leung et al.
Cough (London, England), 3, 10-10 (2007-12-25)
Cough reflex can be induced by the pepper extract capsaicin and by low pH in guinea-pig airways. Transient receptor potential vanniloid-1 (TPRV-1) is expressed in the sensory and afferent nerve fibres in airways. We hypothesized that a novel pyridazinylpiperazine analog
Maria José Garcia-Fernandez et al.
Biofouling, 29(3), 261-271 (2013-02-27)
Prevention and management of wound infections receive a lot of attention, since the presence of micro-organisms interferes with the wound-healing process. The aim of this work was to use cyclodextrins (CDs) to endow hydrogels and gauzes with the ability to
Wayne B Batchelor et al.
Circulation, 106(12), 1470-1476 (2002-09-18)
The relative anti-aggregatory effects of currently prescribed platelet glycoprotein IIb/IIIa receptor antagonists during and after percutaneous coronary intervention for acute coronary syndromes have not been established. We randomized 70 acute coronary syndrome patients undergoing percutaneous coronary intervention to receive abciximab
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