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Merck

746371

Sodium iodide

anhydrous, free-flowing, Redi-Dri, ACS reagent, ≥99.5%

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A propos de cet article

Formule linéaire :
NaI
Numéro CAS:
Poids moléculaire :
149.89
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-679-3
MDL number:
Assay:
≥99.5%
Grade:
ACS reagent, anhydrous
Form:
powder
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InChI key

FVAUCKIRQBBSSJ-UHFFFAOYSA-M

InChI

1S/HI.Na/h1H;/q;+1/p-1

grade

ACS reagent, anhydrous

vapor density

>1 (vs air)

product line

Redi-Dri

assay

≥99.5%

form

powder

quality

free-flowing

impurities

≤0.002% N compounds, ≤0.01% insolubles

pH

6.0-9.0 (25 °C, 5%)

mp

661 °C (lit.)

anion traces

Cl- and Br-: ≤0.01%, iodate (IO3-): ≤3 ppm, phosphate (PO43-): ≤0.001%, sulfate (SO42-): ≤0.005%

cation traces

Ba: ≤0.002%, Ca: ≤0.002%, Fe: ≤5 ppm, K: ≤0.01%, Mg: ≤0.001%, heavy metals (as Pb): ≤5 ppm

Quality Level

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Catégories apparentées

General description

Sodium iodide is an inorganic sodium salt that is commonly used as a source of iodide ions in organic synthesis. It is used in the conversion of alkyl halides and sulfonates into alkyl iodides and aryl iodides via nucleophilic displacement reactions. Additionally, NaI is also used in combination with oxidizing agents for the iodination of organoboranes, phenols, and aromatic compounds.

Application

Sodium iodide can be used in the following:      
  • NaI-AlCl3 is used as a dehydrating agent in the Beckmann rearrangement of ketoximes to anilides.      
  • NaI-cerium chloride supported on silica gel is used as a catalyst for the synthesis of 2,3-dihydro-1H-1,5-benzodiazepines by the reaction of o-phenylenediamines and ketones.      
  • NaI-dichlorodimethylsilane catalytic system is used for the reduction of diarylmethanols to corresponding diarylmethanes.

Features and Benefits

  • Increased efficiency – Eliminates time and effort of loosening hardened powders     
  • Safety – Eliminates tools of force used to break up clumps
  • Ecology – Reduces waste as it does not stick to the packaging      
  • Economy – Faster preparation and solvation increase productivity and reduce costs      
  • Assured Quality – Excellent, expert-tested quality with no anti-caking agents      
  • Flexible volumes – Available from research amounts to scale-up quantities

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

flash_point_f

Not applicable

flash_point_c

Not applicable

target_organs

Thyroid

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Oral

Classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects


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Anke de Vries et al.
Investigative radiology, 50(4), 297-304 (2015-01-01)
The objective of this study was to investigate the feasibility and the accuracy of spectral computed tomography (spectral CT) to determine the tissue concentrations and localization of high-attenuation, iodine-based contrast agents in mice. Iodine tissue concentrations determined with spectral CT
Takuro Isoda et al.
Clinical nuclear medicine, 39(8), 680-684 (2014-07-01)
Many cases of unexpected radioiodine uptake have been reported, including physiological uptake in healthy tissue and in both benign and malignant nonthyroidal lesions. However, iodine uptake in the uterus has not been well assessed. In this article, we systemically analyzed
Dafu Yu et al.
Hormones and behavior, 69, 106-115 (2015-01-28)
Thyroid hormone disorders have long been linked to depression, but the causal relationship between them remains controversial. To address this question, we established rat models of hypothyroidism using (131)iodine ((131)I) and hyperthyroidism using levothyroxine (LT4). Serum free thyroxine (FT4) and
Kerstin Knoop et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 56(4), 600-606 (2015-03-07)
The tumor-homing property of mesenchymal stem cells (MSCs) allows targeted delivery of therapeutic genes into the tumor microenvironment. The application of sodium iodide symporter (NIS) as a theranostic gene allows noninvasive imaging of MSC biodistribution and transgene expression before therapeutic
Yayoi S Kikkawa et al.
Journal of translational medicine, 12, 280-280 (2014-10-05)
A cochlear implant (CI) is an artificial hearing device that can replace a damaged cochlea. The present study examined the use of growth factor-eluting gelatin hydrogel coatings on the electrodes to minimize inner ear trauma during electrode insertion. Insulin-like growth

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