31395
Sulfate de dextran sodium salt from Leuconostoc spp.
Mr ~500,000
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(Leuconostoc spp.)
Quality Level
form
powder
mol wt
Mr ~500,000
composition
Sulfur Content, 16.0-19.0% (dry basis)
manufacturer/tradename
EDQM
useful pH range
6.0-8.0 (10 g/L)
solubility
H2O: freely soluble 50 mg/mL, clear
anion traces
chloride (Cl-): ≤100 mg/kg
cation traces
Ca: ≤200 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤1000 mg/kg, Mg: ≤100 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
storage temp.
room temp
Application
Dextran sulfate sodium salt from Leuconostoc sp. was used as a test compound for studying the heparin and dextran sulphate interaction with alkali ions. It was used for releasing DNA from DNA-histone complexes.
Biochem/physiol Actions
Dextran is a mixture of glucose polymers of varying size and geometry. Dextran in the form of dextran sulfate acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength.The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.
Preparation Note
prepared from dextran with Mr ~500,000
Other Notes
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
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Classe de stockage
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Contenu apparenté
Prevention of venous thromboembolism.
G P Clagett et al.
Chest, 108(4 Suppl), 312S-334S (1995-10-01)
Simon Finfer et al.
The New England journal of medicine, 350(22), 2247-2256 (2004-05-28)
It remains uncertain whether the choice of resuscitation fluid for patients in intensive care units (ICUs) affects survival. We conducted a multicenter, randomized, double-blind trial to compare the effect of fluid resuscitation with albumin or saline on mortality in a
Stefano Casola
Methods in molecular biology (Clifton, N.J.), 271, 91-109 (2004-05-18)
Since its first application in mice almost 10 yr ago, the Cre/loxP has become the system of choice to study gene function in vivo in a cell-type, stage-specific, and inducible manner. This chapter provides a set of updated protocols that