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43410

β-Nicotinamide-adénine-dinucléotide hydrate

greener alternative

≥95% (HPLC)

Synonyme(s) :

β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucléotide, NAD, Nadide

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A propos de cet article

Formule empirique (notation de Hill) :
C21H27N7O14P2 · xH2O
Numéro CAS:
53-84-9
Poids moléculaire :
663.43 (anhydrous basis)
PubChem Substance ID:
57650177
eCl@ss:
39200202
UNSPSC Code:
12352111
NACRES:
NA.55
EC Number:
200-184-4
MDL number:
MFCD00036253
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Quality Level

200

assay

≥95% (HPLC)

form

powder or crystals

greener alternative product characteristics

Waste Prevention
Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

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impurities

≤4% water

color

white to faint yellow

solubility

H2O: 0.1 g/mL at 20 °C, clear, H2O: freely soluble

cation traces

Ca: ≤200 mg/kg, Cd: ≤50 mg/kg, Co: ≤50 mg/kg, Cr: ≤50 mg/kg, Cu: ≤50 mg/kg, Fe: ≤50 mg/kg, K: ≤50 mg/kg, Mg: ≤100 mg/kg, Mn: ≤50 mg/kg, Na: ≤1000 mg/kg, Ni: ≤50 mg/kg, Pb: ≤50 mg/kg, Zn: ≤50 mg/kg

absorbance ratio

A280/260 nm 0.22 ±0.02, A250/260 nm 0.83 ±0.03

greener alternative category

DfS-Developed

storage temp.

−20°C

SMILES string

NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChI key

BAWFJGJZGIEFAR-NNYOXOHSSA-N

Gene Information

human ... ESR1(2099), ESR2(2100)

General description

We are committed to bringing you Greener Alternative Products that adhere to one or more of the 12 Principles of Green Chemistry. Beta-Nicotinamide adenine dinucleotide is a bio-derived redox cofactor that works together with enzymes as part of a biocatalyst system. It can be efficiently recycled in many reactions, enabling selective oxidations while reducing waste and supporting greener, more sustainable chemical processes. Click here for more information.

Application

β-Nicotinamide adenine dinucleotide hydrate has been used as a component of fibroblast cell culture media. It has also been used to study the viability of the cartilage constructs.
β-Nicotinamide adenine dinucleotide hydrate was used as a test compound for studying the structure and electrochemical properties of NADH electrocatalysts.

Biochem/physiol Actions

Accepteur d'électrons
β-Nicotinamide adenine dinucleotide is a cofactor for alcohol dehydrogenase that serves as inhibitory neurotransmitter in visceral smooth muscle.
β-nicotinamide adenine dinucleotide (β-NAD) is a coenzyme present in most living cells. It is implicated in redox reactions and posttranslational modifications. β-NAD also acts as a substrate for various enzymes in several cellular processes.

Packaging

Produit conditionné en fonction du poids solide.

Other Notes

Il s′agit de la forme courante du NAD.

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Classe de stockage

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
BCCN7058
BCCN4177
BCCN2588
BCCM9974
BCCM4492

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Consulter la Bibliothèque de documents

The initial repair response of articular cartilage after mechanically induced damage
van Haaften EE, et al.
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society, 35(6), 1265-1273 (2017)
Structure and Electrochemical Properties of Electrocatalysts for NADH Oxidation.
Rosalba A. Rincon
Electroanalysis, 22, 799-806 (2010)
Extracellular beta-nicotinamide adenine dinucleotide (beta-NAD) promotes the endothelial cell barrier integrity via PKA-and EPAC1/Rac1-dependent actin cytoskeleton rearrangement
Umapathy NS, et al.
Journal of Cellular Physiology, 223(1), 215-223 (2010)
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