D054
R(+)-SCH-23390 hydrochloride
≥98% (HPLC), dopamine receptor antagonist, solid
Synonyme(s) :
R(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
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A propos de cet article
Nom du produit
R(+)-SCH-23390 hydrochloride, ≥98% (HPLC), solid
SMILES string
Cl[H].CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c3ccccc3
InChI
1S/C17H18ClNO.ClH/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12;/h2-6,9-10,15,20H,7-8,11H2,1H3;1H/t15-;/m1./s1
InChI key
OYCAEWMSOPMASE-XFULWGLBSA-N
assay
≥98% (HPLC)
form
solid
optical activity
[α]/D +32.1°, c = 1 in DMF(lit.)
storage condition
desiccated
protect from light
color
white
solubility
H2O: >5 mg/mL
Quality Level
Gene Information
human ... DRD1(1812)
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Catégories apparentées
Application
- for intraperitoneal injection into experimental rats to study the role of D1 receptor in sensitization
- as a D1 receptor-selective antagonist for intracranial drug infusions
- as an antagonist of D1 receptor to study its effect on learning ability in fish
Biochem/physiol Actions
Features and Benefits
Legal Information
Classe de stockage
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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How does the storage temperature relate to shipping conditions?
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
How do I dissolve Product D054, R(+)-SCH-23390 hydrochloride?
The D054 is tested for solublity in water at > 5 mg/mL. The product is also reported to be soluble in DMSO at 3mg/mL, and in ethanol at 2 mg/mL.
What is the solution stability of Product D054, R(+)-SCH-23390 hydrochloride?
Solutions may be stored for approximately 24 hours at 2-8 °C, protected from exposure to light.
Is Product D054, R(+)-SCH-23390 hydrochloride, light sensitive?
Yes, D054 is light sensitive. The powder form of the product, as well as solutions of the product, need to be protected from light.
What is the melting point of Product D054, R(+)-SCH-23390 hydrochloride?
The melting point is 247-248°C.
Is Product D054, R(+)-SCH-23390 hydrochloride, only selective for the D1 dopamine receptor antagonist?
The D054 is a selective D1 dopamine receptor antagonist, but is also selective to the D5.
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