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Merck

E1752

Estrone 3-(β-D-glucuronide) sodium salt

≥99% (HPLC), estrogen metabolite, powder

Synonyme(s) :

1,3,5(10)-Estratrien-17-one 3-glucuronide sodium salt

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A propos de cet article

Formule empirique (notation de Hill) :
C24H29NaO8
Numéro CAS:
Poids moléculaire :
468.47
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Beilstein/REAXYS Number:
6043458
Assay:
≥99% (HPLC)
Form:
powder
Quality level:
Service technique
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Nom du produit

Estrone 3-(β-D-glucuronide) sodium salt,

sterility

non-sterile

Quality Level

assay

≥99% (HPLC)

form

powder

technique(s)

ELISA: suitable

solubility

water: 20 mg/mL, clear, colorless

shipped in

ambient

storage temp.

−20°C

SMILES string

[Na+].[H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc4cc(O[C@@H]5O[C@@H]([C@@H](O)[C@H](O)[C@H]5O)C([O-])=O)ccc24

InChI

1S/C24H30O8.Na/c1-24-9-8-14-13-5-3-12(10-11(13)2-4-15(14)16(24)6-7-17(24)25)31-23-20(28)18(26)19(27)21(32-23)22(29)30;/h3,5,10,14-16,18-21,23,26-28H,2,4,6-9H2,1H3,(H,29,30);/q;+1/p-1/t14-,15-,16+,18+,19+,20-,21+,23-,24+;/m1./s1

InChI key

PBULYLQKWDXDFZ-QHIGSJCSSA-M

Application

Estrone 3-(β-D-glucuronide) sodium salt has been used as a standard:
  • to estimate estrone conjugate (E1Cs) from urine samples by enzyme immunoassays (EIAs)
  • to determine corticosterone metabolites from fecal and water samples by EIA
  • to estimate progesterone and estrogen levels in feces of Chinese goral by EIA

Biochem/physiol Actions

Estrone 3 glucuronide (E3G) is a urinary metabolite of estrogen. Higher levels of estrone 3 glucuronide are observed during the early onset of the fertile period of the menstrual cycle.


Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral



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Rebecca C Miller et al.
Clinical chemistry, 50(5), 924-932 (2004-04-24)
Specific gravity (SG) may perform as well as creatinine (CR) correction for adjusting urinary hormone concentrations, as well as offer some advantages. We compared the two methods and applied them to US and Bangladeshi specimens to evaluate their use in
Andrew H Nagel et al.
Conservation physiology, 7(1), coz074-coz074 (2019-11-19)
This study sought to develop non-invasive techniques to monitor glucocorticoids in captive Necturus as a means to correlate inter-renal gland function in relation to environmental and physiological changes. Six individually housed breeding pairs of captive Necturus beyeri were subjected to
Leonard F Blackwell et al.
Frontiers in public health, 6, 153-153 (2018-06-16)
The patterns of a woman's normal ovarian activity can take many forms from childhood to menopause. These patterns lie on a continuum ranging from no ovarian activity to a fully fertile ovulatory cycle, but among the other defined patterns are