H0267
Hemoglobin A0, Ferrous Stabilized human
lyophilized powder
Synonyme(s) :
Hemoglobin A0 Ferrous Stabilized, Hemoglobin-A0
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A propos de cet article
Numéro CAS:
UNSPSC Code:
12352202
eCl@ss:
42030116
EC Number:
259-278-9
NACRES:
NA.61
MDL number:
Form:
lyophilized powder
Assay:
97-100% (agarose gel electrophoresis)
Biological source:
human
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Laissez-nous vous aiderbiological source
human
assay
97-100% (agarose gel electrophoresis)
form
lyophilized powder
technique(s)
immunofluorescence: suitable
solubility
H2O: soluble 20 mg/mL
suitability
suitable for electrophoresis and chromatography standard
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
human ... HBB(3043)
General description
Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.
has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).
Application
Hemoglobin A0, ferrous stabilized human has been used:
- as the non-fluorescent absorber in the preparation of tissue-mimicking phantoms
- to see how coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype
- to study the interference of hemoglobin (Hb) A0, HbA2, and HbS in the assay of HbF
Hemoglobin A0 was used to see how coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype. It was used in the determination of fetal hemoglobin by time-resolved immunofluorometric assay.
Biochem/physiol Actions
Variation in the haemoglobin (Hb) encoding genes results in haemoglobinopathies such as thalassaemia and atypical structural variants like Hb Lepore and HbE.
Packaging
Package size indicates the amount of hemoglobin as determined by the procedure of Drabkin, D.L., J. Biol. Chem., 164, 703 (1946).
Preparation Note
When reconstituted with buffer, gives >85% ferrous hemoglobin.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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