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Merck

H0396

Hydrocortisone-Water Soluble

BioReagent, suitable for cell culture

Synonyme(s) :

Cyclodextrin-encapsulated hydrocortisone

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A propos de cet article

NACRES:
NA.77
PubChem Substance ID:
24895401
UNSPSC Code:
12352209
MDL number:
MFCD00011654
Biological source:
plant (wild yam)
Form:
crystalline

Principaux documents

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InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

SMILES string

C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)C[C@H](O)[C@H]23

InChI key

JYGXADMDTFJGBT-VWUMJDOOSA-N

biological source

plant (wild yam)

product line

BioReagent

form

crystalline

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 400 mg/mL

shipped in

ambient

storage temp.

room temp

Quality Level

200

Gene Information

human ... ABCB1(5243), CYP3A4(1576), NR3C1(2908), SERPINA6(866)
mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126)
rat ... Ar(24208), Nr3c1(24413)

Catégories apparentées

General description

Hydrocortisone has the potential to induce the formation of blood-brain barrier properties in serum-free culture media. It is recommended for use in epithelial and endothelial adherent cell culture applications.

Application

Hydrocortisone-Water Soluble has been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM)/high glucose medium to culture mammary alveolar (MAC-T) cells. It has also been used to study its effect on cation absorption by semicircular canal duct epithelium via epithelial sodium channel.

Packaging

Package size based on hydrocortisone

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360Df

Hazard Classifications

Repr. 1A

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
0000494105
0000494105
0000493166
0000493166
0000470199

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Consulter la Bibliothèque de documents

P H Wirtz et al.
Heart (British Cardiac Society), 90(8), 853-858 (2004-07-16)
To investigate whether stimulated monocyte cytokine release and its inhibition by glucocorticoids differs between men and women. In vitro monocyte interleukin 6 (IL-6) and tumour necrosis factor alpha (TNFalpha) release after lipopolysaccharide stimulation were assessed with and without co-incubation with
Alexander Kanitz et al.
PloS one, 7(11), e49568-e49568 (2012-11-21)
Vascular endothelial growth factor A (VEGFA) plays a key role in the angiogenesis of human skin. Elevated levels of VEGFA are associated with several pathological conditions, including chronic inflammatory skin diseases and several types of skin cancer. In particular, squamous
Felipe Perozzo Daltoe et al.
Brazilian oral research, 34, e033-e033 (2020-04-09)
The aim of our study was to isolate populations of keratinocyte stem cells based on the expression of cell surface markers and to investigate whether the culture could affect their phenotype. keratinocytes from human oral mucosa were sorted based on
Yohan Choi et al.
Asian-Australasian journal of animal sciences, 25(1), 44-51 (2012-01-01)
Calcium ions play an important role in the establishment and maintenance of pregnancy, but molecular and cellular regulatory mechanisms of calcium ion action in the uterine endometrium are not fully understood in pigs. Previously, we have shown that calcium regulatory
Yohan Choi et al.
Biology of reproduction, 81(6), 1122-1130 (2009-07-31)
Calcium ions have been implicated in the establishment and maintenance of pregnancy, but the regulatory mechanisms of calcium ions in the uterine endometrium and conceptus are not well understood in pigs. Recently, we showed that TRPV6, a calcium ion channel
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