L9170
Lipodisq®
Styrene: Maleic Anhydride Copolymer 3:1, Pre-hydrolyzed, powder, from synthetic
Synonyme(s) :
Lipid nanoparticle, Liposomal delivery system
Se connecter pour consulter les tarifs organisationnels et contractuels.
Sélectionner une taille de conditionnement
A propos de cet article
NACRES:
NA.26
UNSPSC Code:
12352202
Form:
powder
Assay:
98-100%
Biological source:
synthetic
Mol wt:
9500 Da
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aiderService technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aiderbiological source
synthetic
assay
98-100%
form
powder
mol wt
9500 Da
storage condition
(Keep container tightly closed in a dry and well-ventilated place
Keep in a dry place)
storage temp.
room temp
Quality Level
Vous recherchez des produits similaires ? Visite Guide de comparaison des produits
General description
Research area: Cell Structure
Lipodisq® polymers contain styrene and maleic acid monomer units. This product is the pre-hydrolyzed form of the SMA polymer, with styrene and maleic acid monomers. These polymer-lipid complexes are mainly generated by detergent-free methods.
Functional pH range: 6.0 - 9.0
Lipodisq® polymers contain styrene and maleic acid monomer units. This product is the pre-hydrolyzed form of the SMA polymer, with styrene and maleic acid monomers. These polymer-lipid complexes are mainly generated by detergent-free methods.
Functional pH range: 6.0 - 9.0
Application
Lipodisq® reagents are novel polymers derived from styrene and maleic acid. Lipodisq polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents. In general, Lipodisq polymers are potentially useful in mitigating the use of detergents for the solubilization of membrane proteins. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.
Legal Information
Lipodisq is a registered trademark of Malvern Cosmeceutics Limited
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Indra D Sahu et al.
Biochemistry, 52(38), 6627-6632 (2013-08-30)
Pulsed EPR DEER structural studies of membrane proteins in a lipid bilayer have often been hindered by difficulties in extracting accurate distances when compared to those of globular proteins. In this study, we employed a combination of three recently developed
Juan F Bada Juarez et al.
Chemistry and physics of lipids, 222, 51-58 (2019-05-19)
Lipodisq™ nanoparticles have been used to extract surface lipids from the cuticle of two strains (wild type, N2 and the bacteria-resistant strain, agmo-1) of the C. elegans nematode without loss of viability. The extracted lipids were characterized by thin layer
Detergent-Free Formation and Physicochemical Characterization of Nanosized Lipid-Polymer Complexes: Lipodisq
Orwick MC, et al.
Angewandte Chemie (International ed. in English), 51(19), 4653-4657 (2012)
Maria Lyngaas Torgersen et al.
Journal of biomedical nanotechnology, 16(4), 419-431 (2020-09-25)
Many promising pharmaceutically active compounds have low solubility in aqueous environments and their encapsulation into efficient drug delivery vehicles is crucial to increase their bioavailability. Lipodisq nanoparticles are approximately 10 nm in diameter and consist of a circular phospholipid bilayer
Masafumi Tanaka et al.
Chemistry and physics of lipids, 232, 104954-104954 (2020-08-23)
Lipid emulsions are potential carriers for poorly water-soluble drugs. Previously, we revealed that lipid nanoparticles complexed with styrene maleic acid copolymer (SMA) disintegrate under acidic pH. In the present study, SMA-containing lipid emulsions (SMA emulsions) were prepared and their physicochemical
Contenu apparenté
Instructions
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique