M2265
1-Octanoyl-rac-glycerol
≥99%
Synonyme(s) :
Glyceryl 1-monooctanoate, 1-Capryloyl-rac-glycerol, Monocaprylin
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A propos de cet article
Formule empirique (notation de Hill) :
C11H22O4
Numéro CAS:
Poids moléculaire :
218.29
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
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Laissez-nous vous aiderInChI
1S/C11H22O4/c1-2-3-4-5-6-7-11(14)15-9-10(13)8-12/h10,12-13H,2-9H2,1H3
SMILES string
CCCCCCCC(=O)OCC(O)CO
InChI key
GHBFNMLVSPCDGN-UHFFFAOYSA-N
assay
≥99%
form
powder
functional group
ester
lipid type
neutral glycerides
shipped in
ambient
storage temp.
−20°C
Quality Level
Catégories apparentées
Application
- Molecular Simulations and Markov State Modeling of Quorum Sensing Regulators: Research revealed the inactive form of the quorum sensing regulator SdiA in Escherichia coli, offering insights into bacterial communication mechanisms that could be influenced by lipid-based signaling molecules such as 1-Octanoyl-rac-glycerol (Grabski et al., 2021).
Biochem/physiol Actions
Monocaprylin (1-octanoyl-rac-glycerol) is used as an antimicrobial monoglycerin with potential to treat bacteria D congolensis and campylobacter infections and to inactivate E. coli, Listeria and Salmonella on biosurfaces.
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Preeti Wavikar et al.
Journal of pharmaceutical sciences, 106(12), 3613-3622 (2017-09-20)
Present investigation explores the potential of nanostructured lipid carriers (NLCs) for nose to brain delivery of rivastigmine (RV), which is further enhanced by incorporating into an in situ gelling system, increasing retention in nasal cavity. NLCs having particle size of
Abdulsalam M Kassem et al.
Journal of microencapsulation, 34(3), 319-333 (2017-05-10)
The objective of this study was to develop and optimise self-nanoemulsifying drug delivery system (SNEDDS) of atorvastatin calcium (ATC) for improving dissolution rate and eventually oral bioavailability. Ternary phase diagrams were constructed on basis of solubility and emulsification studies. The
Varun Garg et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 109, 297-315 (2017-08-27)
Development of self-nanoemulsifying drug delivery systems (SNEDDS) of polypeptide-k (PPK) is reported with the aim to achieve its oral delivery. Box-Behnken design (BBD) was adopted to develop and optimize the composition of SNEDDS. Oleoyl polyoxyl-6 glycerides (A), Tween 80 (B)
Dong Woo Yeom et al.
Oncotarget, 8(55), 94297-94316 (2017-12-08)
In order to improve the dissolution and oral bioavailability of valsartan (VST), and reduce the required volume for treatment, we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMEDDS) composed of VST (80 mg), Capmul
Dong Jun Shin et al.
Pharmaceutics, 11(2) (2019-02-03)
To improve the dissolution and oral bioavailability of valsartan (VST), we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMED) composed of Capmul® MCM (oil), Tween® 80 (surfactant), Transcutol® P (cosurfactant), and Poloxamer 407 (precipitation inhibitor) but encountered a stability
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