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A propos de cet article
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IF, IHC, WB
Citations:
7
Service technique
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Laissez-nous vous aiderbiological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
predicted mol wt 39-45 kDa
species reactivity
human, rat, mouse
technique(s)
immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ZBP1(81030)
General description
Z-DNA binding protein 1 (ZBP1), also known as interferon (IFN) γ-inducible gene, is a cytoplasmic DNA sensor. It belongs to the family of Z-DNA binding proteins. ZBP1 is majorly expressed in the small intestine and lymphatic tissues. The gene is located on human chromosome 20q13.3.
Immunogen
a 18 amino acid peptide from near the carboxy-terminus of human ZBP1.
Application
Anti-ZBP1 antibody produced in rabbit has been used for western blotting.
Biochem/physiol Actions
Z-DNA binding protein 1 (ZBP1) plays a major role in DNA mediated innate immune responses. It enhances nuclear factor k-light-chain-enhancer of activated B cells (NFκB) activation and proinflammatory cytokine production.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide
Other Notes
The action of this antibody can be blocked using blocking peptide SBP4401.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Classe de stockage
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Molecular Lesions of Insulator CTCF and Its Paralogue CTCFL (BORIS) in Cancer: An Analysis from Published Genomic Studies
Voutsadakis I
High Throughput, 7(4), 30-30 (2018)
Functional roles of pattern recognition receptors that recognize virus nucleic acids in human adipose-derived mesenchymal stem cells
Yu L, et al.
BioMed Research International, 2016 (2016)
ZBP1: innate sensor regulating cell death and inflammation
Kuriakose T and Kanneganti TD
Trends in Immunology, 39(2), 123-134 (2018)