R3501
Rifampicine
≥95% (HPLC), powder or crystals
Synonyme(s) :
3-(4-méthylpipérazinyliminométhyl)rifamycine SV, Rifampine, Rifamycine AMP
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A propos de cet article
Nom du produit
Rifampicine, ≥95% (HPLC), powder or crystals
InChI
1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1
InChI key
JQXXHWHPUNPDRT-WLSIYKJHSA-N
SMILES string
CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(\C=N\N5CCN(C)CC5)c(O)c4c3C2=O
assay
≥95% (HPLC)
form
powder or crystals
color
Reddish-brown
pKa
1.7 (4-hydroxyl group)
7.9 (4-piperazine nitrogen)
pI
4.84
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
viruses
mode of action
protein synthesis | interferes
storage temp.
−20°C
Quality Level
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Application
Biochem/physiol Actions
General description
Other Notes
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Classe de stockage
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
How is the potency determined for Product R3501, Rifampicin?
The potency is determined from a microbiological assay (USP XXII) for antibiotics, a 2-level assay. The test organism is Bacillus subtilis ATCC 6633. The minimum dose is 4.0 μg/ml and the maximum dose is 8.0 μg/ml.
The label advises that I should store Product R3501, Rifampicin, frozen. But when it arrived there was no ice in the package. Why is that?
This product in its powder form is stable for short periods of time (i.e., the shipping process), at ambient temperature. For long term storage it is best to store it at -20°C.
What is the difference between the various Rifampicin products available from Sigma-Aldrich?
Sigma-Aldrich offers several Rifampicin products, each tested and best suited for specific applications. The products range from a general use research grade to sterile powder, to plant culture tested. See individual products for specific details.
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