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S7547

D-sorbitol

Name: <SC>D</SC>-sorbitol
Brand: SIGMA

≥98% (GC), BioXtra

Synonyme(s) :

D-glucitol

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A propos de cet article

Formule empirique (notation de Hill) :

C₆H₁₄O₆

Numéro CAS:

50-70-4

Poids moléculaire :

182.17

UNSPSC Code:

12352201

NACRES:

NA.25

PubChem Substance ID:

24899755

EC Number:

200-061-5

Beilstein/REAXYS Number:

1721899

MDL number:

MFCD00004708

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Propriétés

vapor density

<1 (vs air)

Quality Level

200

vapor pressure

<0.1 mmHg ( 25 °C)

product line

BioXtra

assay

≥98% (GC)

form

powder or chunks

impurities

<0.001% Phosphorus (P), <0.1% Insoluble matter

ign. residue

<0.1%

color

white

useful pH range

5.0-7.0 (25 °C, 182 g/L)

mp

98-100 °C (lit.)

solubility

H₂O: 1 M, clear, colorless (room temperature)

anion traces

chloride (Cl^-): <0.005%, sulfate (SO₄^2-): <0.01%

cation traces

Al: <0.0005%, Ca: <0.0005%, Cu: <0.0005%, Fe: <0.0005%, K: <0.005%, Mg: <0.0005%, NH₄⁺: <0.05%, Na: <0.005%, Pb: <0.001%, Zn: <0.0005%

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

Description

Application

May be used for washing spheroplasts and in isoelectric focusing to minimize endoosmotic flow in agarose gels. May be used to induce osmotic stress.

Biochem/physiol Actions

D-Sorbitol is a sugar alcohol that is commonly used as a sugar substitute. It occurs naturally and is also produced synthetically from glucose. The food industry uses D-sorbitol as an additive in the form of a sweetener, humectant, emulsifier, thickener, or dietary supplement. D-Sorbitol has also been found in cosmetics, paper, and pharmaceuticals. Naturally, D-sorbitol occurs widely in plants via photosynthesis, ranging from algae to higher order fruits of the family Rosaceae.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

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Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Isoelectric focusing.

D E Garfin

Methods in enzymology, 182, 459-477 (1990-01-01)

Tolrestat pharmacokinetic and pharmacodynamic effects on red blood cell sorbitol levels in normal volunteers and in patients with insulin-dependent diabetes.

J M van Griensven et al.

Clinical pharmacology and therapeutics, 58(6), 631-640 (1995-12-01)

To examine the effect of diabetes mellitus on the pharmacokinetics of tolrestat and to investigate its effect on red blood cell sorbitol levels according to a new pharmacodynamic model for this class of drugs. Single and multiple doses of tolrestat

The phosphoinositide PI(3,5)P₂ mediates activation of mammalian but not plant TPC proteins: functional expression of endolysosomal channels in yeast and plant cells.

Anna Boccaccio et al.

Cellular and molecular life sciences : CMLS, 71(21), 4275-4283 (2014-04-29)

Two-pore channel proteins (TPC) encode intracellular ion channels in both animals and plants. In mammalian cells, the two isoforms (TPC1 and TPC2) localize to the endo-lysosomal compartment, whereas the plant TPC1 protein is targeted to the membrane surrounding the large

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