T0397

L-Thyroxine sodium salt pentahydrate

Name: <SC>L</SC>-Thyroxine sodium salt pentahydrate
Brand: SIGMA

γ-irradiated, powder, BioXtra, suitable for cell culture

Synonyme(s) :

3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt, Sodium levothyroxine, T₄

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About This Item

Formule linéaire :

HOC₆H₂I₂OC₆H₂I₂CH₂CH(NH₂)COONa · 5H₂O

Numéro CAS:

6106-07-6

Poids moléculaire :

888.93

UNSPSC Code:

12352209

NACRES:

NA.77

PubChem Substance ID:

24899887

EC Number:

200-221-4

Beilstein/REAXYS Number:

5721845

MDL number:

MFCD00149110

biological source:

synthetic (organic)

form:

powder

assay:

≥98%

Nom du produit

L-Thyroxine sodium salt pentahydrate, γ-irradiated, powder, BioXtra, suitable for cell culture

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1

InChI key

JMHCCAYJTTWMCX-QWPJCUCISA-M

SMILES string

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

biological source

synthetic (organic)

sterility

γ-irradiated

product line

BioXtra

assay

≥98%

form

powder

potency

5-50 ng/mL

technique(s)

cell culture | mammalian: suitable

mp

207-210 (dec.) (lit.)

solubility

cell culture medium: 0.1 mg/mL
H₂O: soluble

storage temp.

−20°C

Quality Level

200

Gene Information

mouse ... Cnr2(12802)
rat ... Cnr1(25248)

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Catégories apparentées

Biochemicals

Cell Culture & Analysis

Cell Culture Supplements & Reagents

High-Purity Biochemicals and Reagents

Hormones

Biochem/physiol Actions

L-Thyroxine (T₄) and triiodo-L-thyronine (T₃) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Physical form

powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw, solution stable 2-8 °C, 30 days

Preparation Note

To prepare 20 μg/ml stock solution, add 50 ml sterile culture medium.

pictograms

GHS08

signalword

Danger

hcodes

H372

pcodes

P260 - P264 - P270 - P314 - P501

Hazard Classifications

STOT RE 1

target_organs

Thyroid,Cardio-vascular system,Kidney

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Lot/Batch Number

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