T2028
(+)-δ-Tocopherol
≥90%
Synonyme(s) :
delta Tocopherol
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A propos de cet article
Formule empirique (notation de Hill) :
C27H46O2
Numéro CAS:
Poids moléculaire :
402.65
PubChem Substance ID:
eCl@ss:
34058016
UNSPSC Code:
12352212
NACRES:
NA.79
EC Number:
204-299-0
MDL number:
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InChI
1S/C27H46O2/c1-20(2)10-7-11-21(3)12-8-13-22(4)14-9-16-27(6)17-15-24-19-25(28)18-23(5)26(24)29-27/h18-22,28H,7-17H2,1-6H3/t21-,22-,27-/m1/s1
InChI key
GZIFEOYASATJEH-VHFRWLAGSA-N
SMILES string
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)cc(C)c2O1
biological source
plant
assay
≥90%
form
liquid
color
light yellow to dark orange
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Application
(+)-δ-Tocopherol has been used as a reference material for its extraction from oil using high performance liquid chromatography (HPLC). It has also been used as a standard to quantify δ-tocopherol in soybean using reverse-phase high performance liquid chromatography.
Biochem/physiol Actions
Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Various isofroms and analogues of tocopherol have opposing and differentiated regulatory activities in vivo.
Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are fat soluble anti-oxidants that protect cell membranes from oxidative damage. δ-T is methylated at the 8-position. It has an anticancer property. δ-T is involved in proinflammatory response initiated by reactive oxygen species. It lowers lipid accumulation and promotes neuronal differentiation. δ-T also has antiangiogenic and natriuretic activities.
Classe de stockage
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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delta-tocopherol is more active than alpha-or gamma-tocopherol in inhibiting lung tumorigenesis in vivo
Li GX, et al.
Cancer Prevention Research (Philadelphia, Pa.), 4(3), 404-413 (2011)
Characterization of oil extracted from the kernel of the fruit of cumare?s palm (Astrocaryum chambira Barret)
Ramirez-Nino M, et al.
Revista Facultad Nacional De Agronomia Medellin, 71(1), 8415-8422 (2018)
Siro Passi et al.
BioFactors (Oxford, England), 18(1-4), 289-297 (2003-12-30)
The concentration of Vitamin E (vit E) and ubiquinone (CoQ10), which together with squalene (SQ), play a key role against external oxidative insult, has been shown to decrease significantly during ageing. The aim of the present study is to inquire
Chandan K Sen et al.
Annals of the New York Academy of Sciences, 1031, 127-142 (2005-03-09)
Vitamin E is essential for normal neurological function. It is the major lipid-soluble, chain-breaking antioxidant in the body, protecting the integrity of membranes by inhibiting lipid peroxidation. Mostly on the basis of symptoms of primary vitamin E deficiency, it has
M G Traber et al.
The American journal of clinical nutrition, 46(3), 488-495 (1987-09-01)
Adipocytes, isolated from human adipose tissue, were disrupted and then centrifuged, resulting in three fractions: oil, interface between the oil and the hypotonic buffer (containing lipid droplets surrounded by unilamellar membranes), and pelleted portion (containing bilayer membranes, intracellular organelles, and
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