T2879
Tyramine hydrochloride
≥98% (TLC), powder, neuromodulator
Synonyme(s) :
4-(2-Aminoethyl)phenol hydrochloride, 4-Hydroxyphenethylamine hydrochloride, Tyrosamine hydrochloride
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A propos de cet article
Formule linéaire :
HOC6H4CH2CH2NH2 · HCl
Numéro CAS:
Poids moléculaire :
173.64
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
200-462-5
MDL number:
Beilstein/REAXYS Number:
3627058
Assay:
≥98%
Service technique
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Laissez-nous vous aiderNom du produit
Tyramine hydrochloride, ≥98%
assay
≥98%
mp
271-274 °C (lit.)
solubility
H2O: soluble 50 mg/ml, clear, colorless to faintly yellow
SMILES string
Cl[H].NCCc1ccc(O)cc1
InChI
1S/C8H11NO.ClH/c9-6-5-7-1-3-8(10)4-2-7;/h1-4,10H,5-6,9H2;1H
InChI key
RNISDHSYKZAWOK-UHFFFAOYSA-N
Gene Information
human ... ADORA2A(135), ADORA2B(136), ADORA3(140)
Application
Tyramine hydrochloride has been:
- coinfused with adenosine in control subjects and patients in order to reduce leg blood flow by 50% without affecting arterial blood pressure
- labelled with fluorescence dyes (Atto 488 and Atto 655) to serve as a substrate for peroxidase in immunofluorescence analysis
- used in dimethylformamide, labelled with 5-(and-6)carboxyfluorescein, succinimidyl ester/biotin to serve as a substrate for peroxidase in tyramide signal amplification
Biochem/physiol Actions
Can enter catecholaminergic terminals and be released as a false transmitter.
Tyramine is a biogenic amine and a neuromodulator localized to the nervous system. Tyrosine decarboxylase catalysis the formation of tyramine from tyrosine. Tyramine is found to be associated with a number of psychiatric disorders. Tyramine ingestion depletes serotonin, epinephrine and norepinephrine reserves. This results in elevated biological events such as cardiovascular function, blood pressure, glucose production and overall metabolism. It also causes depression, migraine and insomnia. Tyramine is present is several food sources. The process of food fermentation and spoilage increases its tyramine content.
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Eighteen Steps to a Healthy Life, 167-167 (2014)
Two functional but noncomplementing Drosophila tyrosine decarboxylase genes distinct roles for neural tyramine and octopamine in female fertility
Cole Shannon H, et al.
Test, 280(15), 14948-14955 (2005)
Immunostaining Enhancement
Immunohistochemistry: Basics and Methods, 47-59 (2009)