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A propos de cet article
Formule empirique (notation de Hill) :
C24H34O4
Numéro CAS:
Poids moléculaire :
386.52
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2066112
Service technique
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pharmaceutical primary standard
API family
medroxyprogesterone
manufacturer/tradename
USP
mp
206-207 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
[H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(OC(C)=O)C(C)=O
InChI
1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1
InChI key
PSGAAPLEWMOORI-PEINSRQWSA-N
Gene Information
human ... PGR(5241)
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Medroxyprogesterone acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Medroxyprogesterone Acetate Injectable Suspension
- Medroxyprogesterone Acetate Tablets
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 4 - Carc. 2
Classe de stockage
11 - Combustible Solids
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Andrew M Kaunitz et al.
Contraception, 77(2), 67-76 (2008-01-30)
While depot medroxyprogesterone acetate (DMPA) is a highly effective contraceptive used by millions of women, its use is associated with bone mineral density (BMD) loss, raising concerns about long-term risk of osteoporosis and/or fractures. We conducted a systematic review of
Cardiovascular effects of medroxyprogesterone acetate and progesterone: a case of mistaken identity?
R Kent Hermsmeyer et al.
Nature clinical practice. Cardiovascular medicine, 5(7), 387-395 (2008-06-04)
Heart disease presentation can differ between the sexes because nonobstructive coronary disease and angina unrelated to exercise are considerably more prevalent in women than in men. When the outcomes of large, randomized, controlled trials failed to demonstrate cardiac risk protection
Lauren J Ralph et al.
The Lancet. Infectious diseases, 15(2), 181-189 (2015-01-13)
The evidence from epidemiological research into whether use of hormonal contraception increases women's risk of HIV acquisition is inconsistent. We did a robust meta-analysis of existing data to provide summary estimates by hormonal contraceptive method which can be used to