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ABT114 Anti-LPA receptor 5 Antibody (GPR92)

Detect the LPA receptor 5 protein using this Anti-LPA receptor 5 (GPR92) validated for use in WB.

Anti-LPA receptor 5 Antibody (GPR92) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: LPAR5, GPR92, GPR93 UniProt Number: Q9H1C0
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ABT114
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT114
      DescriptionAnti-LPA receptor 5 Antibody (GPR92)
      Alternate Names
      • Lysophosphatidic acid receptor 5
      • LPA receptor 5
      • LPA-5
      • G-protein coupled receptor 92
      • G-protein coupled receptor 93
      Background InformationLysophosphatidic acid receptor 5 (LPA receptor 5), also known as GPR92, is a G12/13 and Gq coupled receptor that mediates the signaling of LPA. Ligand binding to LPA receptor 5 may increase intracellular levels of cAMP and calcium, resulting in the activation of a wide range of effector molecules. Recent studies have demonstrated that LPA receptor 5 is abundantly expressed in human mast cells, and mediates the release of the macrophage inflammatory protein-1β (MIP-1β), indicating that LPA receptor 5 may play a role in innate and adaptive immunity.
      References
      Product Information
      FormatAffinity Purified
      Control
      • K562 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect the LPA receptor 5 protein using this Anti-LPA receptor 5 (GPR92) validated for use in WB.
      Key Applications
      • Western Blotting
      Application NotesWestern Blot Analysis: A representative lot detected LPA receptor 5 in non-transfected CHEM-1 cells and CHEM-1 cells transfected with LPAR5(GPR92) (Catalogue. No. HTS209C - Transfected Cell Line).

      Immunocychemistry Analysis: A 1:500 dilution from a representative lot detected LPAR5 in TF1 cells, non-transfected CHEM-1 cells and CHEM-1 cells transfected with LPAR5(GPR92) (Catalogue. No. HTS209C - Transfected Cell Line).

      NOTE: The protein used to make the transfected CHEM1 cell line is full length LPAR5.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the extracellular domain of human LPA receptor 5.
      EpitopeExtracellular domain
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the extracellular domain of LPA receptor 5.
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • LPAR5
      • GPR92
      • GPR93
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~37 kDa observed. The calculated molecular weight of this protein is 41 kDa, but can be observed at ~60 kDa due to high glycosylation.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in K562 cell lysate.

      Western Blot Analysis: 0.2 µg/mL of this antibody detected LPA receptor 5 on 10 µg of K562 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABT114 04053252522819

      Documentation

      Anti-LPA receptor 5 Antibody (GPR92) SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-LPA receptor 5 Antibody (GPR92) Certificates of Analysis

      TitleLot Number
      Anti-LPA receptor 5 (GPR92) - 2453287 2453287
      Anti-LPA receptor 5 (GPR92) - 2465285 2465285
      Anti-LPA receptor 5 (GPR92) - 3277594 3277594
      Anti-LPA receptor 5 (GPR92) - 3407301 3407301
      Anti-LPA receptor 5 (GPR92) - 3420906 3420906
      Anti-LPA receptor 5 (GPR92) - Q2030502 Q2030502
      Anti-LPA receptor 5 (GPR92) -2526211 2526211
      Anti-LPA receptor 5 (GPR92) -2788668 2788668
      Anti-LPA receptor 5 (GPR92) -3165596 3165596
      Anti-LPA receptor 5 (GPR92) Polyclonal Antibody 2910071
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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies