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210150 Cantharidic Acid - CAS 28874-45-5 - Calbiochem

A potent inhibitor of protein phosphatase 2A (IC₅₀ = 50 nM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 5ʹ-3ʹ2,3-Dicarboxy-2,3-dimethyl-1,4-epoxycyclohexane, exo-1,6-Dicarboxy-endo-1,6-dimethyl-7-oxabicylco[2,2,1]heptane

Primary Target: PP2A
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210150
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
28874-45-5C₁₀H₁₄O₅

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210150-10MGCN
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      Description
      OverviewA potent inhibitor of protein phosphatase 2A (IC50 = 50 nM).
      Catalogue Number210150
      Brand Family Calbiochem®
      Synonyms5ʹ-3ʹ2,3-Dicarboxy-2,3-dimethyl-1,4-epoxycyclohexane, exo-1,6-Dicarboxy-endo-1,6-dimethyl-7-oxabicylco[2,2,1]heptane
      References
      ReferencesZhang, Z., et al. 1996. Biochemistry 35, 1606.
      Li, Y.-M., and Casida, J.E. 1992. Proc. Natl. Acad. Sci. USA 89, 11867.
      Graziano, M.J., et al. 1988. Mol. Pharmacol. 33, 706.
      Product Information
      CAS number28874-45-5
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₀H₁₄O₅
      Chemical formulaC₁₀H₁₄O₅
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPP2A
      Primary Target IC<sub>50</sub>50 nM against protein phosphatase 2A
      Purity>95% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliqot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      210150-10MGCN 04055977219142

      Documentation

      Cantharidic Acid - CAS 28874-45-5 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Cantharidic Acid - CAS 28874-45-5 - Calbiochem Certificates of Analysis

      TitleLot Number
      210150

      References

      Reference overview
      Zhang, Z., et al. 1996. Biochemistry 35, 1606.
      Li, Y.-M., and Casida, J.E. 1992. Proc. Natl. Acad. Sci. USA 89, 11867.
      Graziano, M.J., et al. 1988. Mol. Pharmacol. 33, 706.

      Brochure

      Title
      Protein Phosphatases Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-May-2011 JSW
      Synonyms5ʹ-3ʹ2,3-Dicarboxy-2,3-dimethyl-1,4-epoxycyclohexane, exo-1,6-Dicarboxy-endo-1,6-dimethyl-7-oxabicylco[2,2,1]heptane
      DescriptionInhibits protein phosphatase 2A (IC50 = 50 nM).
      FormWhite solid
      CAS number28874-45-5
      Chemical formulaC₁₀H₁₄O₅
      Structure formulaStructure formula
      Purity>95% by TLC
      SolubilityDMSO (25 mg/ml) or warm Ethanol (10 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliqot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesZhang, Z., et al. 1996. Biochemistry 35, 1606.
      Li, Y.-M., and Casida, J.E. 1992. Proc. Natl. Acad. Sci. USA 89, 11867.
      Graziano, M.J., et al. 1988. Mol. Pharmacol. 33, 706.