341578 Fibrinogen, Plasminogen-Depleted, Human Plasma

341578
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341578-500MGCN
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      Glass bottle 500 mg
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      Description
      OverviewNative fibrinogen from human plasma, depleted of plasminogen using a Lys-agarose column. An acute-phase plasma protein found at about 300 mg/dl. Contains ≥ 95% clottable proteins.
      Do not disturb until the fibrinogen is completely solubilized.
      Catalogue Number341578
      Brand Family Calbiochem®
      References
      ReferencesWang, H., et al. 1995. J. Infect. Dis. 171, 85.
      Product Information
      CAS number9001-32-5
      FormLyophilized
      FormulationLyophilized from 20 mM sodium citrate-HCl, pH 7.4.
      Quality LevelMQ200
      Applications
      ApplicationPlasminogen-Depleted fibrinogen is a native fibrinogen from which plasminogen is depleted using a Lys-agarose column. Contains ≥ 95% clottable proteins.
      Biological Information
      Purityhomogeneous by SDS-PAGE. Clottable proteins: ≥95%
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or store at room temperature (20°C) for short-term storage. Stock solutions are stable for up to 4 h at 20°C or for up to 6 months at -70°C. Do not store solutions on ice; precipitation will occur. Stock solutions stored at -70°C should be thawed in a water bath maintained at 37°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Fibrinogen, Plasminogen-Depleted, Human Plasma Certificates of Analysis

      TitleLot Number
      341578

      References

      Reference overview
      Wang, H., et al. 1995. J. Infect. Dis. 171, 85.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-September-2007 RFH
      DescriptionNative fibrinogen from human plasma, depleted of plasminogen using a Lys-agarose column. An acute-phase plasma protein found at about 300 mg/dl. Conversion of soluble fibrinogen to the insoluble clot-forming fibrin is the terminal stage of blood clotting. Clinically, fibrinogen is found at elevated levels during pregnancy, after surgery trauma, or in cases of myocardial infarction. It is found at decreased levels in cases of liver cirrhosis and serum hepatitis. The plasminogen was depleted using a Lys-agarose column.
      FormLyophilized
      FormulationLyophilized from 20 mM sodium citrate-HCl, pH 7.4.
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      CAS number9001-32-5
      Purityhomogeneous by SDS-PAGE. Clottable proteins: ≥95%
      SolubilityH₂O (25 mg/ml). To prevent clot formation, warm the H₂O and the fibrinogen to 37°C prior to dissolution.
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or store at room temperature (20°C) for short-term storage. Stock solutions are stable for up to 4 h at 20°C or for up to 6 months at -70°C. Do not store solutions on ice; precipitation will occur. Stock solutions stored at -70°C should be thawed in a water bath maintained at 37°C.
      Toxicity Harmful
      Merck USA index14, 4071
      ReferencesWang, H., et al. 1995. J. Infect. Dis. 171, 85.