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361555 GSK-3 Inhibitor XIII - CAS 404828-08-6 - Calbiochem

The GSK-3 Inhibitor XIII, also referenced under CAS 404828-08-6, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (5-Methyl-1H-pyrazol-3-yl)-(2-phenylquinazolin-4-yl)amine

Primary Target: GSK-3
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      404828-08-6C₁₈H₁₅N₅
      Description
      OverviewAn aminopyrazole compound that acts as a potent and ATP-binding site inhibitor of GSK-3 with a Ki of 24 nM.
      Catalogue Number361555
      Brand Family Calbiochem®
      Synonyms(5-Methyl-1H-pyrazol-3-yl)-(2-phenylquinazolin-4-yl)amine
      References
      ReferencesPierce, A.C., et al. 2005. J. Med. Chem. 48, 1278.
      Product Information
      CAS number404828-08-6
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₈H₁₅N₅
      Chemical formulaC₁₈H₁₅N₅
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetGSK-3
      Primary Target K<sub>i</sub>24 nM against GSK-3
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Carcinogenic / Teratogenic
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      361555 0

      Documentation

      GSK-3 Inhibitor XIII - CAS 404828-08-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      GSK-3 Inhibitor XIII - CAS 404828-08-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      361555

      References

      Reference overview
      Pierce, A.C., et al. 2005. J. Med. Chem. 48, 1278.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision01-July-2008 RFH
      Synonyms(5-Methyl-1H-pyrazol-3-yl)-(2-phenylquinazolin-4-yl)amine
      DescriptionA potent and ATP-competitive inhibitor of GSK-3 (Ki = 24 nM).
      FormWhite solid
      CAS number404828-08-6
      Chemical formulaC₁₈H₁₅N₅
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Carcinogenic / Teratogenic
      ReferencesPierce, A.C., et al. 2005. J. Med. Chem. 48, 1278.