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EZMCP1-99K10PKRM Human MCP-1 Conferma™ ELISA (10 Pack Bulk)

This Human MCP-1 Conferma™ ELISA kit is used for the quantification of Human MCP-1 in serum, plasma, or culture media samples. One kit is sufficient to measure 37 unknown samples in duplicate.

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EZMCP1-99K10PKRM
96-well strip plate  
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      Overview

      Replacement Information
      Description
      Catalogue NumberEZMCP1-99K10PKRM
      DescriptionHuman MCP-1 Conferma™ ELISA (10 Pack Bulk)
      Background InformationHuman MCP-1 is a chemokine assoscited with the attraction of Monocytes and Basophils to the site of a pathology. In particilar this is a marker of inflammatory disorders. This sandwich ELISA uses our Conferma™ process to ensure a high degree of lot to lot consistency.
      References
      Product Information
      Detection methodColorimetric
      Precision, %
      • Inter-assay: <12.9% CV
      • Intra-assay: <4.9% CV
      Quality LevelMQ200
      Applications
      ApplicationThis Human MCP-1 Conferma™ ELISA kit is used for the quantification of Human MCP-1 in serum, plasma, or culture media samples. One kit is sufficient to measure 37 unknown samples in duplicate.
      Key Applications
      • ELISA
      Application Notes3 hour 45 minute assay, room temperature, 1:5 dilution recommended e.g.30 μL sample + 120μL of diluent (serum, plasma, or tissue culture medium)
      Biological Information
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Analytes Available
      • MCP-1
      Entrez Gene Number
      Entrez Gene Summary This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4
      Gene Symbol
      • HC11
      • MCAF
      • MCP1
      • MCP-1
      • SCYA2
      • GDCF-2
      • SMC-CF
      • HSMCR30
      UniProt Number
      UniProt SummaryFUNCTION: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism.
      SIZE: 212 amino acids; 23,718 Da
      SUBUNIT: Component of a hexamer of two molecules each of IL6, IL6R and IL6ST.
      SUBCELLULAR LOCATION: Extracellular region or secreted
      DISEASE: Rheumatoid arthritis systemic juvenile (RASJ). A IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in HIV-infected men.
      SIMILARITY: Belongs to the IL-6 superfamily.
      Accuracy
      • 84-95%
      Physicochemical Information
      Linearity of DilutionSerum Linearity: 94-106% Serum Parallelism: 91-115% Plasma Linearity: 94-110% Plasma Parallelism: 95-114%
      Standard Curve Range
      • 1.17 pg/mL - 300 pg/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • For research use only. Not for use in diagnostic procedures.
      Storage and Shipping Information
      Packaging Information
      Material Size96-well strip plate
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      EZMCP1-99K10PKRM 04061841718574

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