530748 InSolution™ SRT1720, HCl - CAS 1001645-58-4 - Calbiochem

530748
View Pricing & Availability

Overview

Replacement Information

Key Spec Table

Empirical FormulaCAS #
C₂₅H₂₃N₇OS • 4HCl1001645-58-4

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
5.30748.0001
Retrieving availability...
Limited AvailabilityLimited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Glass bottle 10 mg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity needs to be mulitiple of
      Upon Order Completion More Information
      You Saved ()
       
      Request Pricing
      Description
      OverviewAn enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).

      Please note that the molecular weight for this compound is batch-specific due to variable water content.
      Catalogue Number530748
      Brand Family Calbiochem®
      SynonymsN-(2-(3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-quinolinecarboxamide, 4HCl;, Histone Acetyltransferase Inhibitor XI, p300/CBP Inhibitor IX, SRT1720, HCl InSolution™, HAT Inhibitor XI, SIRT3 Inhibitor II, Sirtuin-3 Inhibitor, SRT1720, HCl
      References
      ReferencesBaur, J.A., et al. 2012. Nat. Rev. Drug Discov. 11, 443.
      Minor, R.K., et al. 2011. Sci. Rep. 1, 70.
      Huber, J.L., et al. 2010. Future Med. Chem. 2, 1751.
      Pacholec, M., et al. 2010. J. Biol. Chem. 285, 8340.
      Jin, L., et al. 2009. Protein Sci. 18, 514.
      Feige, J.N., et al. 2008. Cell Metab. 8, 347.
      Milne, J.C., et al. 2007. Nature 450, 712.
      Product Information
      CAS number1001645-58-4
      FormLiquid
      FormulationA 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl (Cat. No. 567860) in DMSO.
      Hill FormulaC₂₅H₂₃N₇OS • 4HCl
      Chemical formulaC₂₅H₂₃N₇OS • 4HCl
      Hygroscopic Hygroscopic
      ReversibleY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetSIRT3
      Secondary targetp300 HAT
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      InSolution™ SRT1720, HCl - CAS 1001645-58-4 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Baur, J.A., et al. 2012. Nat. Rev. Drug Discov. 11, 443.
      Minor, R.K., et al. 2011. Sci. Rep. 1, 70.
      Huber, J.L., et al. 2010. Future Med. Chem. 2, 1751.
      Pacholec, M., et al. 2010. J. Biol. Chem. 285, 8340.
      Jin, L., et al. 2009. Protein Sci. 18, 514.
      Feige, J.N., et al. 2008. Cell Metab. 8, 347.
      Milne, J.C., et al. 2007. Nature 450, 712.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-June-2014 JSW
      SynonymsN-(2-(3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-quinolinecarboxamide, 4HCl;, Histone Acetyltransferase Inhibitor XI, p300/CBP Inhibitor IX, SRT1720, HCl InSolution™, HAT Inhibitor XI, SIRT3 Inhibitor II, Sirtuin-3 Inhibitor, SRT1720, HCl
      DescriptionAn enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).
      FormLiquid
      FormulationA 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl (Cat. No. 567860) in DMSO.
      Intert gas (Yes/No) Packaged under inert gas
      CAS number1001645-58-4
      Chemical formulaC₂₅H₂₃N₇OS • 4HCl
      Purity≥98% by HPLC
      Storage ≤ -70°C
      Hygroscopic
      Protect from light
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesBaur, J.A., et al. 2012. Nat. Rev. Drug Discov. 11, 443.
      Minor, R.K., et al. 2011. Sci. Rep. 1, 70.
      Huber, J.L., et al. 2010. Future Med. Chem. 2, 1751.
      Pacholec, M., et al. 2010. J. Biol. Chem. 285, 8340.
      Jin, L., et al. 2009. Protein Sci. 18, 514.
      Feige, J.N., et al. 2008. Cell Metab. 8, 347.
      Milne, J.C., et al. 2007. Nature 450, 712.