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100820 Methenamine silver plating kit acc. to Gomori

for the detection of argent-affine structures in histological tissue

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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100820
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      1.00820.0007
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          Description
          Catalogue Number100820
          DescriptionMethenamine silver plating kit acc. to Gomori
          OverviewThe Methenamine silver plating kit acc. to Gomori - for the detection of argent-affine structures in histological tissue, is used for human-medical cell diagnosis and serves the purpose of the histological investigation of sample material of human origin, for example histological sections of e. g. the kidney, the intestine, or the liver. The periodic acid Schiff (PAS) reaction is often used for the visualization of basal membranes, fungal elements, or other argentaffin structures in the tissue. However, the Methenamine silver plating acc. to Gomori results in better and richer-in-contrast visualization of these target structures.
          In the first step of the silver plating, the Periodic acid oxidizes the 1,2-glycols in the tissue to aldehydes. Due to the incubation with Methenamin-borat silver nitrate solution, these aldehydes are reduced and in turn are responsible for the reduction of the silver ions to metallic silver. This silver will appear black. The subsequent treatment of the tissue with gold chloride intensifies the staining of the argent-affinic structures and concurrently reduces the background staining, and the washing with sodium thiosulfate solution will remove the excess of silver-gold complexes. Like this, the target structures will exhibit a dark brown to black color and all other structures will be counter-stained with light green SF.
          The package is sufficient for up to 50 applications. This product is registered as IVD and CE marked. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
          References
          Product Information
          HS Code3212 90 00
          Quality LevelMQ400
          Applications
          Applicationfor the detection of argent-affine structures in histological tissue
          Biological Information
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Statement(s)H315: Causes skin irritation.
          H317: May cause an allergic skin reaction.
          H319: Causes serious eye irritation.
          H360FD: May damage fertility. May damage the unborn child.
          H373: May cause damage to organs through prolonged or repeated exposure if swallowed.
          H410: Very toxic to aquatic life with long lasting effects.
          Precautionary Statement(s)P202: Do not handle until all safety precautions have been read and understood.
          P273: Avoid release to the environment.
          P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
          P302 + P352: IF ON SKIN: Wash with plenty of water.
          P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
          P308 + P313: IF exposed or concerned: Get medical advice/ attention.
          Signal WordDanger
          Storage class6.1C Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
          WGKWGK 3 highly hazardous to water
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +15°C to +25°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 3316 Chemie-Testsatz, 9, II
          Declaration (transport by air) IATA-DGRUN 3316 CHEMICAL KIT, 9, II
          Declaration (transport by sea) IMDG-CodeUN 3316 CHEMICAL KIT, 9, II
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          1.00820.0001 04022536764719
          1.00820.0007 04061838824431

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