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540217 PTP LYP Inhibitor - Calbiochem

The PTP LYP Inhibitor controls the biological activity of PTP LYP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

PTP LYP Inhibitor - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (2-pyridine)(Ph)₂P-Au-Cl, HePTP Inhibitor III, PTP Inhibitor XXVIII, PTP-PEST Inhibitor

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540217
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₁₇H₁₄AuClNP

Pricing & Availability

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540217-5MGCN
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      		 5 mg
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      Description
      OverviewA cell-permeable, Au(I)-phosphine complex that acts as selective inhibitor of lymphoid tyrosine phosphatase (LYP) (IC50= 1.5 µM) and has a ~10-fold selectivity for LYP over PTP-PEST, HePTP, and CD45 in both JTAg cells and primary mouse thymocytes.
      Catalogue Number540217
      Brand Family Calbiochem®
      Synonyms(2-pyridine)(Ph)₂P-Au-Cl, HePTP Inhibitor III, PTP Inhibitor XXVIII, PTP-PEST Inhibitor
      References
      ReferencesKarver, M.R., et al. 2009. J. Med. Chem. 52, 6912.
      Product Information
      FormWhite solid
      Hill FormulaC₁₇H₁₄AuClNP
      Chemical formulaC₁₇H₁₄AuClNP
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥ 95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      540217-5MGCN 04055977268713

      Documentation

      PTP LYP Inhibitor - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      PTP LYP Inhibitor - Calbiochem Certificates of Analysis

      TitleLot Number
      540217

      References

      Reference overview
      Karver, M.R., et al. 2009. J. Med. Chem. 52, 6912.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision23-February-2011 RFH
      Synonyms(2-pyridine)(Ph)₂P-Au-Cl, HePTP Inhibitor III, PTP Inhibitor XXVIII, PTP-PEST Inhibitor
      DescriptionA cell-permeable, Au(I)-phosphine complex that acts as selective inhibitor of lymphoid tyrosine phosphatase (LYP) (IC50= 1.5 µM) and has a ~10-fold selectivity for LYP over PTP-PEST, HePTP, and CD45 in both JTAg cells and primary mouse thymocytes.
      FormWhite solid
      Chemical formulaC₁₇H₁₄AuClNP
      Structure formulaStructure formula
      Purity≥ 95% by HPLC
      SolubilityDMSO (50 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesKarver, M.R., et al. 2009. J. Med. Chem. 52, 6912.