526511 Phytohemagglutinin-M, Phaseolus vulgaris

526511
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526511-20MGCN
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      Glass bottle 20 mg
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      Description
      OverviewStimulates the proliferation of human lymphocytes and mouse splenic T cells. Causes agglutination titers of 1:128 in tests using 2% solution of type A red blood cells.
      Catalogue Number526511
      Brand Family Calbiochem®
      References
      ReferencesDupis, G., and Leclair, B. 1982. FEBS Lett. 144, 29.
      Felsted, R.L., et al. 1977. J. Biol. Chem. 252, 2967.
      Product Information
      CAS number9008-97-3
      FormLyophilized
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityOptimum activity for the stimulation of proliferation of lymphocytes is at 5-10 µg/ml.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSTJ3470000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Phytohemagglutinin-M, Phaseolus vulgaris SDS

      Title

      Safety Data Sheet (SDS) 

      Phytohemagglutinin-M, Phaseolus vulgaris Certificates of Analysis

      TitleLot Number
      526511

      References

      Reference overview
      Dupis, G., and Leclair, B. 1982. FEBS Lett. 144, 29.
      Felsted, R.L., et al. 1977. J. Biol. Chem. 252, 2967.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-May-2018 JSW
      DescriptionT-cell mitogen that stimulates the proliferation of human lymphocytes and mouse splenic T-cells. PHA is a mixture of tetramers consisting of combinations of two subunits, E and L, with different biological activity. E-4 isolectin has low mitogenic activity and high erythroagglutinating activity. L-4 isolectin has high mitogenic and leukoagglutinating activities and low erythroagglutinating activity. Causes agglutination titers of 1:128 in tests that use a 2% solution of type A red blood cells. Inhibited by N-acetyl-D-galactosamine, peptides containing the sequence NANA-D-Gal-(1 → 3,4), GlcNAcα(1 → 2), or Man α(1 → 2)Man.
      FormLyophilized
      CAS number9008-97-3
      RTECSTJ3470000
      Biological activityOptimum activity for the stimulation of proliferation of lymphocytes is at 5-10 µg/ml.
      SolubilitySterile redistilled H₂O (2-10 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Toxicity Standard Handling
      Merck USA index14, 5429
      ReferencesDupis, G., and Leclair, B. 1982. FEBS Lett. 144, 29.
      Felsted, R.L., et al. 1977. J. Biol. Chem. 252, 2967.